Product Overview

Chemical Name: 4,6-Dichloro-2-(methylthio)pyrimidine
Molecular Formula: C₅H₄Cl₂N₂S
Molecular Weight: 195.07 g/mol
CAS Number: 6299-25-8
Synonyms: 4,6-Dichloropyrimidine methyl sulphide; 4,6-Dichloro-2-methylmercaptopyrimidine

A key intermediate for pharmaceutical and agrochemical synthesis, this compound is favored by fine chemicals suppliers in China for its reactivity in nucleophilic substitution reactions.

Physicochemical Properties

Appearance: White to off-white crystalline powder
Odor: Characteristic sulfurous odor
Density: 1.48 g/cm³ (estimated)
Melting Point: 98-102°C
Boiling Point: 285°C (decomposes)
Solubility: Soluble in DMSO, DMF; slightly soluble in ethanol; insoluble in water

Stable under ambient conditions but moisture-sensitive. Requires storage in cool, dry environments.

Applications

• Pharmaceutical Intermediate: Core building block for antiviral and anticancer drug candidates
• Agrochemical Synthesis: Precursor for fungicides and plant growth regulators
• Chemical Research: Versatile scaffold for heterocyclic compound development

As a leading pharmaceutical intermediates supplier in China, we provide this product with exceptional batch-to-batch consistency for critical synthesis processes.

Quality Standards

Purity (HPLC): ≥98.5%
Moisture Content: ≤0.5% (Karl Fischer)
Residual Solvents: Meets ICH Q3C guidelines
Heavy Metals: ≤10 ppm
Chloride Content: 34.5-36.5% (theoretical 35.8%)

Certificates of Analysis available for each batch. Custom purity grades (99%+) available for specialty chemical manufacturers in China.

Packaging & Transportation

Primary Packaging: 25 kg polyethylene-lined fiber drums
Custom Options: 1 kg, 5 kg glass containers for R&D quantities
Storage: Keep sealed at 2-8°C in ventilated area
Transport Classification: Non-hazardous (ADR/IMDG/IATA exempt)
Shelf Life: 24 months when stored properly

All shipments include moisture-proof packaging and temperature monitoring for sensitive intermediates.

Our Capabilities

Specializing in complex chemical synthesis under challenging conditions:
• Process Expertise: High-temperature (>200°C) & high-pressure (>50 bar) reactions
• Advanced Technologies: Continuous flow nitration & oxidation systems
• Scale-Up Services: From kg-scale R&D to 100 MT production campaigns
• Core Competencies: Brominated compounds, nitrogen heterocycles, sulfur-containing intermediates

We partner with agrochemical intermediates manufacturers in China to deliver cost-effective solutions for multi-step syntheses (≤5 steps). Contact us for custom synthesis projects or process optimization needs.

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