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NEWS CONTENT
5-(4-Fluorophenyl)-5-oxopentanoic Acid: Pharmaceutical Intermediate & Synthesis Guide
Publish Date:2025-03-01      Click:234

Product Overview



Chemical Name: 5-(4-Fluorophenyl)-5-oxopentanoic acid
Synonyms: 4-(4-Fluorobenzoyl)butyric acid (multiple listings)
Molecular Formula: C11H9FO3
Molecular Weight: 208.19 g/mol
CAS Number: 149437-76-3

Physicochemical Properties



Appearance: White to off-white crystalline powder
Odor: Odorless
Density: 1.32 g/cm³ (predicted)
Melting Point: 148-152°C
Solubility: Soluble in DMSO, methanol; sparingly soluble in water

Applications



Key intermediate for synthesizing antidepressants and anti-inflammatory agents
Building block for fluorinated active pharmaceutical ingredients (APIs)
Used in continuous flow chemistry processes for scale-up production
High-purity fluorobenzoyl derivatives supplier in China for research and commercial applications

Quality Specifications



Purity (HPLC): ≥98.5%
Residual Solvents: <0.1% (ICH Q3C compliant)
Heavy Metals: <10 ppm
Water Content: <0.5% (Karl Fischer)

Packaging & Transportation



Primary Packaging: Double-layer polyethylene bags
Secondary Packaging: 25 kg sealed fiber drums
Storage: 2-8°C in dry environment
Transport Classification: Non-hazardous (ADR 2.2/IMDG Code non-regulated)

Our Expertise



Specialized in continuous flow process development China for hazardous reactions
Core capabilities: High-temperature/pressure reactions, nitration, oxidation
Production scale: 100 kg to 100 MT annual capacity
Focus chemistry: Bromides, heterocyclic compounds (thiophene, indole derivatives)
Custom fluorinated intermediates manufacturer China with in-house pilot plant


Keywords: fluorobenzoyl butyric acid supplier China, pharmaceutical intermediates manufacturer, continuous flow reaction technology China
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