Introduction to 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one, commonly known by its CAS number 79-50-5, is a versatile chemical compound with a wide range of applications. Also referred to as DL-Pantolactone, this compound is identified by several aliases including (+-)-dihydro-3-hydroxy-4,4-dimethylfuran-2(3H)-one, 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (+-)-, DL-alpha-Hydroxy-beta,beta-dimethyl-alpha-butyrolactone, DL-PANTOYL LACTONE, and D-(-)-Pantoyl lactone. This article delves into the chemical properties, applications, and usage of this compound, highlighting its importance in various industries.

Chemical Properties and Structure

3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one is a gamma-lactone with the molecular formula C6H10O3 and a molecular weight of 130.14. Its structure consists of a five-membered ring with a hydroxyl group at the 3-position and two methyl groups at the 4-position. The compound is a white to off-white solid with a melting point ranging from 74-78°C and a boiling point of 121°C at 11 mmHg. It is soluble in water, alcohol, ether, and benzene, making it highly versatile for various chemical processes.

The compound's stability is notable, although it is unstable in aqueous solutions. Its pKa value is predicted to be 13.12±0.40, indicating its potential for use in reactions involving acidic or basic conditions. The chemical's refractive index is 1.497-1.501, and it has a flash point of 122°C, which is crucial for safety considerations in handling and storage.

Applications in Cosmetics and Skincare

One of the primary applications of 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one is in the cosmetics and skincare industry. As a safe moisturizer, it is not acne-causing and generally has no effect on pregnant women. It serves as a conditioning agent, helping to soften and moisturize the skin. Additionally, it has been found to have a soothing effect on sensitive skin and can aid in skin whitening.

The compound's ability to be easily absorbed by the hair makes it a valuable ingredient in hair care products. It stimulates the proliferation of hair follicle cells, promoting hair growth and improving hair texture. Its use in cosmetics and skincare products underscores its role as a 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one manufacturer in China, ensuring high-quality standards for these applications.

Industrial and Pharmaceutical Uses

Beyond cosmetics, 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one finds significant use in the industrial and pharmaceutical sectors. In the pharmaceutical industry, it is used as a precursor in the synthesis of various drugs, including those related to pantothenic acid, which is a vital component of coenzyme A. The compound's role in the synthesis of 3,5-dinitrobenzoyl-DL-pantolactone further highlights its importance in pharmaceutical research and development.

Industrially, the compound is utilized in the production of other chemicals and as a raw material for various chemical processes. Its versatility in high-temperature and high-pressure reactions, as well as its use in nitration and oxidation processes, makes it a valuable asset for 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one suppliers in China who cater to diverse industrial needs.

Safety and Handling

When handling 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one, it is essential to adhere to safety guidelines. The compound is classified under the GHS07 symbol with a warning signal word. It poses a risk of causing eye irritation (H319), and precautionary measures include wearing protective gloves and eye protection (P280), washing hands thoroughly after handling (P264), and rinsing eyes with water if exposed (P305+P351+P338).

Storage should be in a cool, dry place, sealed to prevent moisture exposure. The compound's sensitivity to humidity necessitates careful handling to maintain its integrity and effectiveness. As a 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. ensures that all safety protocols are followed to deliver a high-quality product.

Conclusion

3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one (CAS: 79-50-5) is a multifaceted compound with significant applications in cosmetics, pharmaceuticals, and industrial processes. Its chemical properties, including solubility and stability, make it an ideal candidate for various uses. As a leading 3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality products that meet the stringent demands of these industries.

Our Other Services

At NINGBO INNO PHARMCHEM CO.,LTD., our main business scope includes the research and development, as well as the production of fine chemicals and pharmaceutical intermediates. We specialize in continuous flow process development and equipment manufacturing, with our own pilot plant and external large-scale production platforms. Our expertise covers a range of reaction types such as high temperature, high pressure, nitration, oxidation, and continuous distillation.

Our R&D and manufacturing services encompass fine chemicals and pharmaceutical intermediates like bromide, boric acid, thiophene, indole, imidazole, thiazole, piperazine, and pyrazine compounds, with production volumes ranging from tons to hundreds of tons. We focus on products with volumes between 100 kgs to 100 MT per year, typically involving up to 5 synthetic steps. If you have any other needs, please feel free to contact us.

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