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N-[(2R,3S)-2-(2,5-Difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamic acid 1,1-dimethylethyl ester

CAS：
951127-25-6
Synonym：
N-[(2R,3S)-2-(2,5-Difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamic acid 1,1-dimethylethyl ester
MK-3102 intermediate I
Omarigliptin intermediate I
tert-butyl [(2R,3S)-5-oxo-2-(2,5-difluorophenyl)tetradihydro-2H-pyran-3-yl]carbamate
tert-butyl [(2R,3S)-5-oxo-2-(2,5-difluorophenyl)tetrahydro-2H-pyran-3-yl]carbamate
tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pvran-3 yl]carbamate

Details

Chemical Name: N-[(2R,3S)-2-(2,5-Difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamic acid 1,1-dimethylethyl ester
CAS.NO: 951127-25-6
Synonyms:MK-3102 intermediate I
Omarigliptin intermediate I
tert-butyl [(2R,3S)-5-oxo-2-(2,5-difluorophenyl)tetradihydro-2H-pyran-3-yl]carbamate
tert-butyl [(2R,3S)-5-oxo-2-(2,5-difluorophenyl)tetrahydro-2H-pyran-3-yl]carbamate
tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pvran-3 yl]carbamate

Molecular Formula: C16H19F2NO4
Molecular Weight: 327.32300

Physical and Chemical Properties:
Density:1.3±0.1 g/cm3
Boiling point: 433.4±45.0 °C at 760 mmHg
Melting point: /
Flash point: 215.9±28.7 °C
Refractive index: 1.516

Specification:
Appearance: White powder
Purity: >99％
Water:0.5% Max.

Packing:
25kg cardboard drum or according to customer specified requirements
Storage:Stored in a well-closed container at low temperature, keep away from moisture, heat and light.
Application:Intermediates of Oralliptin CAS:1226781-44-7 .

Since the establishment of the company, it has established good and stable cooperative relations with many domestic and foreign pharmaceutical companies.In addition to our core competence in the standard unit operations of organic chemical synthesis, we offer specialised reaction technology, including innovative organometallic synthesis, catalytic transfer hydrogenation and the various operations required for synthesis of chiral compounds.We have leading technology and rich synthesis experience, and our professional R&D team is currently in the leading position in China.Synthesis of reference compounds, intermediates, drug candidates, impurities and metabolites for customers with a range of milligrams to kilograms (including GMP quality).We use our research in assisting customers to solve their most challenging problems and unique opportunities.

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Laboratory in Ningbo
Our company's R&D company, Ningbo Gino Chemical Co., Ltd. was established in December 2011. we have several fume hoods and kilogram laboratory, and have purchased 20L, 50L reactors and as a preliminary pilot manufacturing of the products. At the same time, We mobilized external resources to establish a pilot facility in Henan Zhumadian and Anhui Anqing, and cooperating with Shandong Zibo and Jiangsu Changzhou factories as a large production facility for our products.

Factory in Shanxi Province
At the end of 2017, We invested workshop in Xinjiang County Longzhou Chemical Co., Ltd., Xinjiang County Coal Mine Park, Yuncheng, Shanxi. The first phase of the reactors were 30* 2000L~5000L, The contract output value is 50 million annually, factory has passed the audit from public listed company domestic and abroad.

Factory in Shandong Province
The production base of liquid rectification chemical products located in Liaocheng, Shandong Province is the main outsourcing production base of our company. The products are sold to leading enterprises and listed companies in the carcass industry for many years. The production, quality and service are stable, delivery is timely, and some individual products are covering 90% of the market.

Factory in Henan Province
In year 2020, We invested workshop in Henan province, the workshop consists of 50*2000L~5000L reactors, The types of reactions that can be manufacturer there are: bromination, cyanidation, and conventional reactions.

Disclaimer: Certain products are for research use only. Not for diagnostic or therapeutic use. Not for human use. INNOPHARMCHEM does not sell to individuals. INNOPHARMCHEM does not warrant that the use or sale of the products delivered under will not infringe the claims of any China or other patents covering the product itself or the use thereof in combination with other products or the operation of any process.

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