Sourcing Methyl 4-bromo-3-nitrobenzoate (CAS 2363-16-8): A Guide for Industrial and Research Needs
For industries and research laboratories requiring advanced chemical intermediates, sourcing the right materials is a critical step in ensuring project success. Methyl 4-bromo-3-nitrobenzoate, identified by its CAS number 2363-16-8, is a compound that frequently appears in synthesis pathways for pharmaceuticals, fine chemicals, and specialty materials. This article serves as a guide to understanding its properties and the considerations involved in sourcing this vital intermediate.
Methyl 4-bromo-3-nitrobenzoate is an aromatic compound characterized by a methyl ester group, a bromine atom, and a nitro group attached to a benzene ring. Its physical properties, such as a melting point typically around 102-103°C and a density of approximately 1.673 g/cm³, are important indicators of its purity and handling characteristics. The compound is often supplied as a white to orange or green crystalline powder. Its chemical reactivity is primarily driven by the bromine atom, which is susceptible to nucleophilic substitution and palladium-catalyzed cross-coupling reactions, and the nitro group, which can be reduced to an amine.
The applications of Methyl 4-bromo-3-nitrobenzoate are diverse. In pharmaceutical synthesis, it serves as a key building block for creating complex drug molecules, leveraging its functional groups for targeted modifications. Its role in Suzuki coupling reactions allows for the facile construction of carbon-carbon bonds, essential for synthesizing biaryl compounds that are prevalent in many drug structures. Beyond pharmaceuticals, it finds use in the development of advanced materials and other specialty chemicals due to its versatile chemical structure.
When it comes to sourcing Methyl 4-bromo-3-nitrobenzoate, reliability and quality are paramount. Many chemical manufacturers and suppliers offer this compound, with availability ranging from small laboratory quantities to bulk industrial orders. It is advisable to research and compare different suppliers based on their reputation, product purity specifications, lead times, and pricing. Many companies now facilitate the purchase of Methyl 4-bromo-3-nitrobenzoate online, providing easy access for researchers and procurement managers alike.
For industrial applications, securing a consistent supply of high-purity Methyl 4-bromo-3-nitrobenzoate is crucial for maintaining production quality and efficiency. For research purposes, having access to reliable sources ensures that experiments can be conducted with reproducible results. Understanding the compound's synthesis pathways and its reactivity allows researchers to effectively integrate it into their synthetic strategies. Ultimately, proper sourcing of Methyl 4-bromo-3-nitrobenzoate is a fundamental step towards achieving successful outcomes in chemical synthesis and product development.
Perspectives & Insights
Chem Catalyst Pro
“Its physical properties, such as a melting point typically around 102-103°C and a density of approximately 1.”
Agile Thinker 7
“Its chemical reactivity is primarily driven by the bromine atom, which is susceptible to nucleophilic substitution and palladium-catalyzed cross-coupling reactions, and the nitro group, which can be reduced to an amine.”
Logic Spark 24
“In pharmaceutical synthesis, it serves as a key building block for creating complex drug molecules, leveraging its functional groups for targeted modifications.”