Understanding HPMC Viscosity Grades for Pharmaceutical Applications
Hydroxypropyl Methyl Cellulose (HPMC) is a versatile excipient whose properties are significantly influenced by its viscosity grade. For pharmaceutical applications, selecting the correct viscosity is critical for achieving desired outcomes in tablet coating, binding, and controlled release. As a dedicated HPMC manufacturer, we aim to demystify these viscosity grades and guide you in making informed choices.
HPMC is typically categorized by its viscosity, measured in millipascal-seconds (mPa·s) for a specified concentration in water. For instance, common viscosity grades range from low (e.g., E5, E15) to high (e.g., K4M, K100M). These variations in viscosity directly correlate with the polymer's molecular weight and chain length, impacting its functional performance in a formulation.
In tablet film coating, lower viscosity HPMC grades (e.g., E5, E15) are often preferred. They form thin, uniform films that are easily applied and do not unduly affect the tablet's disintegration or dissolution characteristics. These grades provide good coating efficiency and result in clear, robust films that protect the tablet core from environmental factors. Buyers seeking these grades can count on us as a reliable HPMC supplier to provide consistent quality.
For controlled-release applications, higher viscosity grades of HPMC are generally employed. These polymers form a more viscous gel matrix when hydrated, which effectively slows down the diffusion of the active pharmaceutical ingredient (API). Grades like K4M or K100M are instrumental in achieving sustained drug release over extended periods, improving patient compliance. Our expertise as an HPMC manufacturer allows us to offer a comprehensive range of these high-viscosity grades, crucial for advanced drug delivery systems.
As a leading HPMC supplier in China, we provide detailed technical specifications for all our products, including viscosity profiles. Whether you need HPMC for immediate release, sustained release, or as a binder, consulting with our experienced team can help you select the optimal viscosity grade. Partner with us to ensure the success of your pharmaceutical formulations.
Perspectives & Insights
Silicon Analyst 88
“Buyers seeking these grades can count on us as a reliable HPMC supplier to provide consistent quality.”
Quantum Seeker Pro
“For controlled-release applications, higher viscosity grades of HPMC are generally employed.”
Bio Reader 7
“These polymers form a more viscous gel matrix when hydrated, which effectively slows down the diffusion of the active pharmaceutical ingredient (API).”