Azosemide: A Potent Diuretic Agent for Research and Pharmaceutical Applications
Explore the intricate workings and therapeutic potential of Azosemide, a key compound in understanding renal function and treating cardiovascular conditions.
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Azosemide
Azosemide (CAS 27589-33-9) is a significant high-ceiling loop diuretic, recognized for its potent inhibition of the sodium-potassium-chloride cotransporter (NKCC1). This characteristic makes it an invaluable tool for researchers investigating renal physiology, electrolyte balance, and the molecular basis of diuretic resistance.
- Explore the diuretic pharmacology research with Azosemide's NKCC1 inhibitor properties. This compound is instrumental in dissecting the complex mechanisms of kidney function and fluid regulation.
- Understand the azosemide CAS 27589-33-9 through detailed chemical properties. Its molecular formula C12H11ClN6O2S2 and molecular weight of 370.84 g/mol are crucial for accurate experimental design.
- Investigate the loop diuretic mechanism by studying Azosemide. Its application in treating edematous states and hypertension offers insights into cardiovascular health.
- Discover the diverse applications of this sulfonamide diuretic. From fundamental renal function research to potential therapeutic uses, Azosemide serves a broad scientific purpose.
Key Advantages
Potent NKCC1 Inhibition
Azosemide's strong inhibition of the NKCC1 transporter is critical for detailed renal physiology studies, offering precise control in experiments aimed at understanding ion transport.
Versatile Research Tool
As a well-characterized loop diuretic, it's a staple in experiments focusing on electrolyte balance and the management of edematous conditions, supporting broad electrolyte balance studies.
Pharmaceutical Relevance
Its established role in treating hypertension and edematous states makes it a compound of interest for pharmaceutical development and research into cardiovascular drug development.
Key Applications
Renal Physiology Research
Researchers utilize Azosemide to investigate the intricate mechanisms of the loop of Henle and its role in fluid and electrolyte excretion, supporting renal function research.
Pharmacological Studies
Its defined NKCC1 inhibitor activity makes it a key compound in studies exploring diuretic action and its effects on cellular transport pathways.
Cardiovascular Health
Azosemide is studied for its efficacy in managing conditions like congestive heart failure and hypertension, contributing to research in cardiovascular drug development.
Chemical Synthesis and Analysis
Understanding the azosemide chemical properties is vital for its synthesis, quality control, and application in various laboratory settings.