Calcifediol: Understanding 25-Hydroxyvitamin D3
Explore the biological significance and health applications of this key vitamin D metabolite.
Get a Quote & SampleProduct Core Value

Calcifediol
Calcifediol, also known as 25-hydroxyvitamin D3, is a critical intermediate in the vitamin D metabolic pathway. It serves as the primary circulating form of vitamin D in the body, making its measurement a standard for assessing vitamin D status.
- Understanding vitamin D metabolism is key to overall health, and Calcifediol plays a central role.
- The 25-hydroxyvitamin D3 level is a reliable indicator of how much vitamin D your body has and how effective supplementation might be.
- Calcifediol is vital as it can be further converted into calcitriol, the active form of vitamin D, essential for calcium absorption and bone health.
- As an oral medication, Calcifediol offers a direct way to improve vitamin D levels for those with deficiencies or specific health concerns.
Key Advantages
Accurate Vitamin D Status Assessment
Measuring 25-hydroxyvitamin D3 levels provides a direct insight into your body's vitamin D sufficiency, guiding personalized health strategies.
Effective Supplementation
Calcifediol supplementation can be more potent than cholecalciferol in raising vitamin D levels, offering a targeted approach for vitamin D deficiency treatment.
Supports Active Hormone Production
As a precursor, Calcifediol directly supports the synthesis of calcitriol, the hormonally active form of vitamin D, crucial for numerous bodily functions.
Key Applications
Health Monitoring
Blood tests for 25-hydroxyvitamin D3 are the standard for diagnosing vitamin D deficiency or sufficiency.
Therapeutic Supplementation
Used as an oral medication to correct vitamin D deficiency and manage conditions like secondary hyperparathyroidism.
Nutritional Research
Investigating the role of vitamin D metabolites in various physiological processes and disease prevention.
Pharmaceutical Development
Serving as a reference material and active ingredient in the development of new treatments related to vitamin D metabolism.