Diphenhydramine Hydrochloride: High-Purity API for Pharmaceutical and Research Applications
A vital pharmaceutical intermediate for allergy relief, insomnia, and cold symptom management.
Get a Quote & SampleProduct Core Value

Diphenhydramine Hydrochloride
Diphenhydramine Hydrochloride is a first-generation antihistamine renowned for its sedative and anticholinergic properties. This high-purity API is extensively used in pharmaceuticals to alleviate allergy symptoms, aid in short-term insomnia treatment, manage motion sickness, and relieve common cold symptoms. Its stability as a crystalline powder and its wide distribution within the body make it a cornerstone in various therapeutic formulations.
- Discover the extensive uses of diphenhydramine hydrochloride for allergy relief, addressing a common need for effective antihistaminic solutions.
- Explore the sedative properties of diphenhydramine hydrochloride, offering a potential solution for short-term insomnia management.
- Learn about its application as a pharmaceutical intermediate, crucial for the synthesis of various medicinal products.
- Understand the importance of safe customs clearance for diphenhydramine hcl, ensuring its efficient import and availability for research and manufacturing.
Key Advantages
High Purity and Quality
Ensuring pharmaceutical-grade quality, this compound offers >99% purity, critical for reliable research and drug manufacturing processes, meeting USP/BP standards.
Versatile Pharmaceutical Applications
Beyond its antihistamine properties, it serves as a potent sedative and anticholinergic, making it valuable for multiple therapeutic areas including cough and cold relief.
Established Safety Profile
With a long history of use, Diphenhydramine Hydrochloride provides a well-understood safety profile when used as directed, though caution with certain contraindications is advised.
Key Applications
Allergy Treatment
Effectively manages allergic reactions, including hay fever and skin manifestations like urticaria, by blocking histamine H1 receptors.
Insomnia Relief
Its sedative properties make it a common ingredient in over-the-counter sleep aids for short-term management of insomnia.
Motion Sickness Management
Used for the active treatment and prevention of motion sickness, offering relief from nausea and dizziness.
Cold Symptom Relief
Helps alleviate common cold symptoms such as sneezing, runny nose, and watery eyes.