High Purity Ponatinib Hydrochloride: Advanced Tyrosine Kinase Inhibitor for Leukemia Treatment
Discover the potent multi-targeted tyrosine kinase inhibitor for advanced leukemia therapies.
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Ponatinib Hydrochloride
Ponatinib Hydrochloride (CAS 1114544-31-8) is a powerful, multi-targeted tyrosine kinase inhibitor crucial for treating complex leukemias, including those resistant to other therapies. Its high purity and specific mechanism of action make it a vital compound in advanced cancer research and treatment development.
- Leverage the potent anti-BCR-ABL activity, including against the T315I mutation, for effective leukemia treatment.
- Explore the antiangiogenic and antineoplastic properties to advance oncology drug development.
- Utilize high purity pharmaceutical grade Ponatinib Hydrochloride for reliable research and synthesis.
- Understand the detailed in vitro and in vivo activities to guide your research into targeted cancer therapies.
Key Advantages
Targeted Mechanism
Ponatinib's ability to inhibit both native and mutated forms of BCR-ABL, alongside other kinases like FGFR1 and VEGFR2, positions it as a critical tool for addressing drug-resistant cancers and exploring novel treatment pathways in oncology drug development.
Research Purity
With purity exceeding 99%, this compound ensures accurate and reproducible results in complex scientific research, supporting the reliable sourcing of pharmaceutical intermediates for critical applications.
Broad Applicability
The comprehensive data on Ponatinib Hydrochloride's performance in various cell lines and animal models aids researchers in understanding its potential across diverse hematologic malignancies research and other related fields.
Key Applications
Leukemia Treatment
Ponatinib Hydrochloride is essential for patients with chronic myeloid leukemia (CML) and Ph+ ALL, especially those resistant to prior treatments, offering a targeted approach in hematologic malignancies research.
Cancer Therapy Research
Its multi-targeted kinase inhibition profile makes it a key compound for exploring new antineoplastic strategies and understanding cancer cell signaling pathways in oncology drug development.
Pharmaceutical Intermediate Sourcing
High-purity Ponatinib Hydrochloride serves as a critical intermediate for further synthesis and development of novel pharmaceutical agents, supporting the broader biotech research chemicals market.
Drug Discovery
Researchers utilize this compound to study kinase inhibition mechanisms and develop next-generation targeted cancer therapies, advancing the field of kinase inhibitor applications.
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