Unlocking Digestive Health: Linaclotide Acetate (CAS 851199-59-2) for IBS-C & CIC Management
Discover Linaclotide Acetate, a leading peptide API proven to revolutionize the management of Irritable Bowel Syndrome with Constipation and Chronic Idiopathic Constipation.
Get a Quote & SampleLinaclotide Acetate: Revolutionizing Gastrointestinal Health

Linaclotide Acetate
Linaclotide (CAS 851199-59-2) is a first-in-class guanylate cyclase-C (GC-C) agonist, celebrated for its unique mechanism of action in addressing complex gastrointestinal conditions. As a high-purity pharmaceutical intermediate, it stands at the forefront of innovative digestive health solutions.
- Targeted Action: As a potent guanylate cyclase C agonist, Linaclotide selectively binds to intestinal receptors, initiating a cascade of beneficial physiological responses.
- Effective Symptom Relief: Clinically proven to significantly alleviate abdominal pain and constipation, especially for linaclotide for IBS-C treatment and Chronic Idiopathic Constipation.
- Enhanced Intestinal Function: Promotes increased fluid secretion and accelerated bowel transit, providing comprehensive relief for patients with chronic idiopathic constipation linaclotide needs.
- Minimal Systemic Absorption: Its peptide structure ensures low systemic exposure, contributing to a favorable safety profile, making it a reliable Peptide API.
Key Advantages of Choosing Linaclotide
Superior Efficacy in GI Disorders
Linaclotide offers superior efficacy in managing symptoms associated with IBS-C treatment and Chronic Idiopathic Constipation, improving patient quality of life.
Advanced Pharmacological Mechanism
Its unique action as a guanylate cyclase C agonist ensures a targeted approach, distinguishing it from conventional therapies and providing lasting relief.
Reliable & Safe Profile
With a well-established safety profile and minimal systemic absorption, Linaclotide is a trusted choice for long-term management of chronic gastrointestinal conditions.
Key Applications
Irritable Bowel Syndrome with Constipation (IBS-C)
Linaclotide is a cornerstone in the treatment of Irritable Bowel Syndrome with Constipation (IBS-C), significantly improving both abdominal pain and bowel frequency.
Chronic Idiopathic Constipation (CIC)
For patients suffering from Chronic Idiopathic Constipation (CIC), Linaclotide provides effective relief by enhancing intestinal motility and fluid secretion.
Beyond Common GI Disorders
Emerging research shows potential for Linaclotide in other challenging conditions like gastroparesis and certain manifestations of ulcerative colitis.
Cosmetic & Research Applications
Beyond pharmaceutical uses, its high-purity cosmetic grade linaclotide peptides make it valuable for advanced research and specialized cosmetic formulations.