Obeticholic Acid: A Deep Dive into Its Pharmaceutical Applications
Exploring the efficacy and safety of this potent FXR agonist for liver health and beyond.
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Obeticholic Acid
Obeticholic Acid is a potent and selective farnesoid X receptor (FXR) agonist with significant therapeutic potential in treating liver diseases. It acts by modulating bile acid homeostasis, inflammation, and fibrosis, offering a novel approach to managing conditions like primary biliary cholangitis and nonalcoholic steatohepatitis.
- Discover the efficacy of Obeticholic Acid for NASH patients, as detailed in recent meta-analyses and clinical trials.
- Understand the comprehensive obeticholic acid safety profile, including its notable side effects like pruritus.
- Learn about the mechanism of action for this key FXR agonist in liver treatment.
- Explore options to buy Obeticholic Acid online from trusted suppliers.
Key Advantages
Enhanced Liver Function
Obeticholic acid demonstrates a significant ability to reduce key liver enzyme markers such as ALT, AST, ALP, and GGT, contributing to improved liver health.
Histological Improvement
The compound promotes substantial improvements in histological markers for NASH, including fibrosis, steatosis, lobular inflammation, and hepatocellular ballooning.
Targeted FXR Agonism
As a selective FXR agonist, it offers a targeted therapeutic approach for various metabolic and liver-related disorders, making it a valuable tool in drug discovery.
Key Applications
Pharmaceutical Manufacturing
Used as an active pharmaceutical ingredient (API) in the development of treatments for liver diseases, underscoring its role in innovative drug manufacturing.
Medical Research
A critical compound for preclinical and clinical research into cholestatic liver conditions, metabolic syndrome, and other FXR-mediated diseases.
Chemical Synthesis
Serves as a high-purity chemical intermediate in advanced organic synthesis, contributing to the development of complex molecules.
Drug Discovery & Development
Essential for exploring new therapeutic avenues and understanding disease mechanisms, particularly in gastroenterology and hepatology.