PNC-27: A Novel Anti-Cancer Peptide Targeting Cancer Cell Membranes for Selective Necrosis
Discover the cutting-edge potential of PNC-27, a synthetic peptide engineered to selectively destroy cancer cells.
Get a Quote & SampleProduct Core Value

PNC-27 Peptide
PNC-27 is a groundbreaking synthetic anti-cancer peptide that leverages a unique mechanism to combat cancer. It selectively binds to the HDM-2 protein, which is highly expressed on the surface of cancer cells. This targeted interaction disrupts the cell membrane, leading to the formation of pores and subsequent tumor cell necrosis. Crucially, this process is independent of p53 activity and has shown minimal impact on normal cells, distinguishing it from many conventional cancer treatments.
- PNC-27 Anti-Cancer Peptide Mechanism: Explores how PNC-27's interaction with HDM-2 on cancer cell membranes triggers cell death.
- PNC-27 Peptide Cancer Cell Death Insights: Details the process by which PNC-27 leads to targeted destruction of malignant cells.
- PNC-27 HDM-2 Protein Interaction Studies: Focuses on the critical binding of PNC-27 to the HDM-2 protein as the basis for its selective action.
- PNC-27 Peptide for Research Applications: Highlights the use of PNC-27 as a valuable tool in ongoing cancer research and therapeutic development.
Key Advantages of PNC-27
Selective Cancer Cell Targeting
The synthetic anti-cancer peptide PNC-27 exhibits remarkable selectivity, primarily targeting cancer cells due to its interaction with HDM-2 protein.
Mechanism of Tumor Necrosis
PNC-27 induces tumor cell necrosis by forming transmembrane pores, offering a distinct pathway for cancer cell elimination compared to apoptosis.
P53-Independent Action
The peptide's anti-cancer efficacy is not reliant on the p53 pathway, suggesting broader applicability across different cancer types.
Key Applications
Cancer Research
PNC-27's targeted mechanism makes it a valuable tool for studying cancer cell membrane interactions and developing new therapeutic strategies.
Oncology Drug Development
The peptide's unique properties position it as a promising candidate for novel oncology drug development, potentially overcoming resistance issues.
Therapeutic Agent Studies
Researchers are investigating PNC-27 for its potential role in improving antitumor effects and enhancing existing treatment protocols.
Biotechnology Innovation
As a synthetic peptide, PNC-27 represents a significant advancement in biotechnology, offering new avenues for disease treatment.
Related Technical Articles & Resources
Why Choose Us?
Leverage our expertise and state-of-the-art infrastructure to accelerate your journey from discovery to commercial success.
Global Experience
With 20 years of R&D, manufacturing, and sales experience, we proudly serve clients across 60 countries and regions worldwide.
Advanced Facilities
Our in-house R&D laboratory, pilot platform, and large-scale production workshop are equipped to meet the audit requirements of global customers.
Seamless Scalability
We facilitate a perfect transition from small-scale lab requirements (grams) to full commercialization (hundreds of tons).