Roxadustat (808118-40-3): High-Purity API for Pharmaceutical Applications
Discover the critical role of this HIF prolyl-hydroxylase inhibitor in advanced anemia treatment.
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HIF Prolyl Hydroxylase Inhibitor
This compound is a potent, orally administered small molecule inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase. It plays a crucial role in stabilizing HIF and stimulating the endogenous production of erythropoietin (EPO), thereby enhancing hemoglobin and red blood cell production. Its primary application is in the treatment of anemia associated with chronic kidney disease (CKD).
- Discover the critical role of Roxadustat in advanced anemia treatment for chronic kidney disease patients.
- Explore the HIF prolyl hydroxylase inhibitor mechanism of action that boosts red blood cell production.
- Learn about the pharmaceutical API synthesis processes for high-purity active pharmaceutical ingredients.
- Find reliable suppliers for Roxadustat CAS 808118-40-3, essential for drug development.
Advantages
Enhanced Efficacy
As a HIF prolyl-hydroxylase inhibitor, this compound offers a novel therapeutic approach for anemia, distinct from traditional ESAs. Its ability to stabilize HIF leads to a coordinated erythropoietic response.
High Purity and Quality
Sourced from reputable manufacturers, the API boasts high purity, crucial for pharmaceutical applications and meeting stringent quality standards. Reliable buying Roxadustat online ensures consistent product quality.
Therapeutic Versatility
Beyond CKD-related anemia, research indicates potential applications in other conditions, making it a valuable asset for pharmaceutical companies engaged in drug development. Exploring pharmaceutical intermediate sourcing is key.
Key Applications
Anemia Treatment
Used for treating symptomatic anemia in adults with chronic kidney disease, both dialysis-dependent and non-dialysis-dependent patients. This highlights the importance of securing a stable Roxadustat API synthesis supply.
Pharmaceutical Research
Serves as a critical research chemical and reference standard for pharmaceutical companies developing new anemia therapies and studying the HIF pathway. Sourcing this compound is vital for research endeavors.
Drug Discovery & Development
Its unique mechanism makes it a subject of interest in drug discovery, particularly for conditions related to hypoxia and erythropoiesis. Effective pharmaceutical intermediate sourcing is key here.
Biochemical Assays
Utilized in various biochemical assays and studies to understand the complex mechanisms of HIF stabilization and its downstream effects on cellular processes.