Streptomycin Sulfate: A Comprehensive Overview

Discover the critical role of this powerful antibiotic in fighting severe infections and its applications in biotechnology.

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Key Advantages

Broad-Spectrum Efficacy

This antibiotic offers broad-spectrum efficacy against various Gram-negative bacteria and mycobacteria, crucial for addressing complex infections like plague and tularemia.

Biotechnology Applications

Beyond its medical use, streptomycin sulfate is invaluable in biotechnology for protein purification and as a selective agent in cell culture media, aiding research and development.

Established Medical Use

With a long history of use, streptomycin sulfate is a well-established treatment option, particularly in cases where other antibiotics are ineffective or resistance has developed, such as in treating tuberculosis.

Key Applications

Medical Treatment

Primary use as an antibiotic for severe bacterial infections including tuberculosis, plague, brucellosis, tularemia, and endocarditis.

Cell Culture

Used in combination with penicillin to prevent bacterial contamination in eukaryotic cell cultures, ensuring cell line viability and experimental accuracy.

Protein Purification

Aids in removing nucleic acids and associated proteins from biological extracts by binding to ribosomes and precipitating them from solution.

Pesticide Use

Applied in agriculture to control bacterial diseases in crops, notably fire blight on apple and pear trees.