Urokinase (9039-53-6): A Comprehensive Guide to its Properties, Applications, and Industrial Significance
Discover the fibrinolytic power and research applications of Urokinase, a vital enzyme in medicine and biotechnology.
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Urokinase
Urokinase, identified by CAS 9039-53-6, is a significant enzyme with potent fibrinolytic capabilities. It directly activates plasminogen into plasmin, a key enzyme in breaking down blood clots. Unlike other thrombolytic agents, urokinase is derived from human sources (urine or kidney cells), making it non-antigenic and suitable for patients with sensitivities to other treatments. Its mechanism of action is crucial in dissolving fibrin, thereby treating conditions caused by blood clots and serving as a valuable tool in scientific research, particularly in constructing animal models for diseases.
- Explore the Urokinase enzyme mechanism and its role in fibrinolysis for a deeper understanding of its therapeutic potential.
- Investigate the diverse Urokinase CAS 9039-53-6 applications in treating thromboembolic diseases and its utility in various research fields.
- Learn about the Urokinase production process, from its extraction to purification, ensuring high quality for research and clinical use.
- Understand the Urokinase therapeutic use in managing conditions like DVT and PE, highlighting its importance in cardiovascular health.
Key Advantages of Urokinase
Direct Plasminogen Activation
Urokinase is renowned for its ability to directly convert plasminogen to plasmin, facilitating efficient clot lysis. This direct activation pathway is a significant aspect of the Urokinase enzyme mechanism.
Non-Antigenic Nature
Sourced from human origins, Urokinase is non-antigenic, offering a safer alternative for patients who may have developed antibodies to other thrombolytic agents like streptokinase.
Versatile Research Tool
The utility of Urokinase for animal modeling, particularly in cardiovascular research, makes it an indispensable reagent for scientists studying thrombosis and related conditions.
Key Applications
Thrombolytic Therapy
Urokinase serves as a critical thrombolytic agent, used in the treatment of conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and peripheral vascular occlusion.
Medical Research
Its role in activating plasminogen makes it valuable for in vitro studies and understanding fibrinolytic pathways. Researchers often buy Urokinase online for these purposes.
Animal Modeling
Urokinase is frequently employed to induce thrombosis models in animals, aiding the study of disease progression and the efficacy of new therapeutic interventions.
Biotechnology
As a potent enzyme, Urokinase finds applications in various biotechnological processes and as a component in diagnostic kits.
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