Fmoc-Lys(Ac)-OH: Your Key to Advanced Peptide Synthesis
Discover the essential properties and applications of this vital Fmoc-protected amino acid derivative.
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Fmoc-Lys(Ac)-OH
Fmoc-Lys(Ac)-OH (CAS 159766-56-0) is a critical component in modern peptide synthesis, specifically utilized in Fmoc solid-phase peptide synthesis (SPPS). Its primary role is to introduce the N-epsilon-acetyl-L-lysine residue into peptide chains, a modification vital for various biological functions and research applications.
- Fmoc-Lys(Ac)-OH peptide synthesis: This compound is specifically designed for use in the Fmoc SPPS methodology, enabling the efficient and controlled incorporation of acetylated lysine.
- CAS 159766-56-0: Serving as a crucial identifier, this CAS number ensures the correct sourcing and identification of this high-quality amino acid derivative.
- Acetyl-L-lysine Fmoc derivative: As a protected form of acetyl-L-lysine, it offers stability and reactivity tailored for complex peptide construction projects.
- N-epsilon-acetyl-L-lysine synthesis: Researchers leverage this building block for the targeted synthesis of peptides containing this specific post-translational modification.
Advantages It Brings
Enhanced Peptide Modification
The use of this acetylated lysine derivative allows for the precise introduction of acetylation, a common modification that impacts protein function and stability, aiding in complex peptide chemistry research.
Reliable Fmoc SPPS Reagents
As a high-purity Fmoc-amino acids, it ensures consistent and high yields in Fmoc solid-phase peptide synthesis, reducing experimental variability.
Facilitates Proteomics Research
By enabling the synthesis of modified peptides, it is instrumental in advancing proteomics research and understanding cellular signaling pathways.
Key Applications
Peptide Synthesis
Essential for the construction of custom peptides, this amino acid derivative is a cornerstone for pharmaceutical and biotechnological research, contributing to novel therapeutic development.
Fmoc SPPS
The compound is an integral part of the Fmoc solid-phase peptide synthesis workflow, providing a protected lysine moiety that can be selectively deprotected and coupled.
Introducing N-epsilon-acetyl-lysine
Researchers utilize it to create peptides with specific acetylation patterns on the lysine side chain, mimicking natural post-translational modifications.
Amino Acid Building Blocks
As a versatile building block, it finds application in academic and industrial laboratories for a wide array of biochemical synthesis projects.