Within the realm of pharmaceutical intermediates and APIs, understanding the nuances between closely related compounds is crucial for effective application and procurement. Carbazochrome and Carbazochrome Sodium Sulfonate are two such compounds, both known for their hemostatic properties but differing in their chemical structure, solubility, and specific applications. This article clarifies these distinctions, providing valuable insights for industry professionals.

Carbazochrome, identified by CAS number 69-81-8, is the base compound. It is a synthetic organic molecule derived from the oxidation of epinephrine. In its pure form, Carbazochrome is typically a dark orange to very dark orange solid. Its solubility profile indicates it is slightly soluble in water and more soluble in DMSO. As a pharmaceutical intermediate carbazochrome, it serves as a building block for more complex derivatives and finds direct application as a hemostatic agent by reinforcing capillary walls and reducing vascular permeability.

Carbazochrome Sodium Sulfonate, on the other hand, is a salt derivative of Carbazochrome. The addition of the sodium sulfonate group significantly enhances its water solubility. This increased solubility makes it easier to formulate and administer, particularly in injectable forms or solutions where rapid dissolution is required. While it shares the fundamental hemostatic action of Carbazochrome by improving capillary integrity, its enhanced solubility profile often leads to its preference in specific pharmaceutical preparations.

The applications of Carbazochrome Sodium Sulfonate are closely related to its parent compound but are often favored in scenarios requiring better aqueous formulation. It is used to prevent and treat capillary bleeding and to reduce vascular permeability. Importantly, it has been utilized in contexts like the prevention of dengue shock syndrome, where its ease of administration in solution can be advantageous. Both compounds are manufactured under strict quality controls by reputable suppliers, with Carbazochrome manufacturers China being a significant global source for both.

When buyers look to buy Carbazochrome powder or its derivatives, understanding these differences is key. The choice between Carbazochrome and Carbazochrome Sodium Sulfonate may depend on the specific formulation requirements, desired route of administration, and cost-effectiveness. The Carbazochrome API price can vary between the two forms due to the additional processing steps involved in creating the sodium sulfonate derivative. Nevertheless, both are critical components in the pharmaceutical industry, valued for their hemostatic capabilities.

In conclusion, while both Carbazochrome and Carbazochrome Sodium Sulfonate offer valuable hemostatic effects, their differing solubility and formulation characteristics cater to distinct pharmaceutical needs. Recognizing these differences is vital for informed procurement and optimal application in medical treatments.