At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing detailed insights into the pharmaceutical chemicals we supply, including Probenecid (CAS 57-66-9). Understanding the chemical profile, synonyms, and potential synthesis routes is crucial for researchers and manufacturers working with this important active pharmaceutical ingredient.

Probenecid, with the CAS number 57-66-9, is chemically known as 4-'((dipropylamino)sulfonyl)-benzoic acid or 4-(Dipropylsulfamoyl)benzoic acid. It is also recognized by various synonyms such as Apurina, Benemid, and Benuryl, underscoring its established presence in the pharmaceutical industry. Its molecular formula is C13H19NO4S, and it has a molecular weight of approximately 285.36 g/mol. The EINECS number for Probenecid is 200-344-3.

From a physical perspective, Probenecid typically presents as a white or off-white crystalline powder. Its melting point is generally reported in the range of 194-196°C, and it has a density of about 1.2483. In terms of solubility, Probenecid is slightly soluble in DMSO and methanol but is nearly insoluble in water. It readily dissolves in alkaline solutions, such as sodium hydroxide, but remains largely insoluble in acidic media. These solubility characteristics are important considerations for formulation development.

The synthesis of Probenecid often involves several key chemical intermediates and reactions. While specific proprietary synthesis pathways may vary among manufacturers, common routes involve starting materials like p-toluenesulfonamide or 4-(chlorosulfonyl)benzoic acid, which then undergo reactions with dipropylamine. The meticulous control of reaction conditions and purification steps is essential to achieve the high purity (>99%) required for pharmaceutical grade Probenecid. NINGBO INNO PHARMCHEM CO.,LTD. ensures that all our supplied Probenecid meets stringent quality control standards, derived from well-established manufacturing processes.

For those involved in pharmaceutical research and development, sourcing reliable pharmaceutical intermediates and APIs is critical. NINGBO INNO PHARMCHEM CO.,LTD. provides Probenecid, supporting diverse applications from gout treatment to enhancing antibiotic performance. Our commitment to quality ensures that our clients can confidently buy Probenecid, knowing they are obtaining a product that meets rigorous industry specifications. Understanding the chemical nature of Probenecid is the first step towards unlocking its full therapeutic potential.