NINGBO INNO PHARMCHEM CO.,LTD. provides insights into the fundamental chemical characteristics and therapeutic mechanisms of Diltiazem Hydrochloride. This compound, chemically known as C22H26N2O4S and identified by CAS number 42399-41-7, has a molecular weight of approximately 414.52 g/mol. Its physical presentation is typically a white to off-white crystalline powder, with a melting point generally around 210-214°C. These physical and chemical properties are crucial for its formulation into various pharmaceutical dosage forms, including tablets and extended-release capsules.

The therapeutic efficacy of Diltiazem Hydrochloride stems from its classification as a calcium channel blocker. It selectively inhibits the influx of extracellular calcium ions across the membranes of myocardial cells and vascular smooth muscle cells, without significantly affecting serum calcium levels. This action has a dual effect: it reduces myocardial contractility and heart rate, and it causes vasodilation in peripheral and coronary arteries. These combined effects contribute to its widespread use in managing hypertension, thereby lowering blood pressure, and in treating angina by increasing oxygen supply to the myocardium while reducing demand.

Understanding the precise chemical structure and properties of Diltiazem Hydrochloride is vital for pharmaceutical formulators and quality control specialists. NINGBO INNO PHARMCHEM CO.,LTD. ensures that its Diltiazem Hydrochloride API meets stringent purity standards, often exceeding 98%, with well-controlled impurity profiles. This commitment to quality is essential for the safety and efficacy of the final drug product. The consistent chemical identity and pharmacological action of Diltiazem Hydrochloride make it a reliable choice for physicians treating a broad spectrum of cardiovascular ailments, reinforcing its importance in the pharmaceutical industry.

As a leading supplier, NINGBO INNO PHARMCHEM CO.,LTD. plays a role in making this critical API accessible to global pharmaceutical markets. The detailed chemical profile and established therapeutic action of Diltiazem Hydrochloride underscore its significance in modern medicine and its continued relevance in managing chronic cardiovascular conditions.