Neostigmine Methyl Sulfate, identified by its CAS number 51-60-5, is a chemical compound with significant pharmacological properties. Chemically, it is a reversible inhibitor of acetylcholinesterase. Unlike its tertiary amine counterpart, physostigmine, Neostigmine Methyl Sulfate, being a quaternary amine, exhibits limited penetration across the blood-brain barrier. This characteristic is crucial as it localizes its primary effects to the peripheral nervous system, minimizing central nervous system side effects and making it a safer option for specific therapeutic interventions. Understanding these nuances is key for researchers and formulators looking for Neostigmine Methyl Sulfate pharmaceutical powder.

The synthesis of Neostigmine Methyl Sulfate typically involves the reaction of 3-dimethylaminophenol with N-dimethylcarbamoyl chloride, followed by alkylation with dimethyl sulfate. This controlled process results in a compound with a characteristic red powder appearance and a melting point around 126°C. The purity of this compound is paramount, especially when it is to be used as a Neostigmine Methyl Sulfate USP Standard. Suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensure that their product meets these exacting standards, providing the reliability needed for pharmaceutical manufacturing and research.

The applications of Neostigmine Methyl Sulfate extend beyond its well-established roles. It is extensively used in the reversal of neuromuscular blockade in anesthesia and in the treatment of Myasthenia Gravis and Ogilvie syndrome. Furthermore, ongoing research explores its potential in managing other conditions that involve cholinergic dysregulation. The availability of this compound as a research chemical, or for bulk purchase by companies seeking to buy Neostigmine Methyl Sulfate raw material, highlights its importance across various sectors of the healthcare industry.

For businesses in the pharmaceutical sector, sourcing a consistent and high-quality supply of high purity Neostigmine Methyl Sulfate is critical for product development and manufacturing. NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable provider, ensuring that every batch of Neostigmine Methyl Sulfate meets the highest quality benchmarks. Exploring the advantages of working with established suppliers like NINGBO INNO PHARMCHEM CO.,LTD. can streamline the procurement process and guarantee the integrity of the final pharmaceutical products derived from this essential chemical.