Diphenhydramine Hydrochloride is a chemical compound that plays a significant role in the pharmaceutical landscape. With the CAS number 147-24-0, it is widely recognized as a first-generation antihistamine, but its chemical characteristics lend themselves to a broader range of applications. Understanding its molecular formula, C17H22ClNO, and its physical properties, such as being a white powder, is fundamental for those involved in its production, formulation, or research.

The chemical structure of Diphenhydramine Hydrochloride imparts several key properties. Its molecular weight and specific chemical bonds enable it to interact effectively with histamine H1 receptors, blocking their activation and thereby preventing or alleviating allergic responses. This direct antagonism of histamine is the basis for its primary use in treating allergic conditions, from rhinitis to skin rashes. The compound's ability to pass through the blood-brain barrier also accounts for its central nervous system effects.

The applications of Diphenhydramine Hydrochloride are extensive. As an antihistamine, it is invaluable for managing the symptoms of allergies, including sneezing, itching, and watery eyes. Beyond this primary role, its sedative properties make it a common ingredient in sleep aids, helping individuals who suffer from insomnia to fall asleep more easily. The antiemetic and anticholinergic actions are also noteworthy; it can help combat nausea and vomiting, particularly motion sickness, and can influence smooth muscle contractions and secretions.

For pharmaceutical manufacturers, the availability of high-purity Diphenhydramine Hydrochloride powder is critical. Sourcing from reliable suppliers who can provide documentation regarding purity levels (e.g., 99%) and certifications (e.g., GMP, USP) is essential for ensuring product quality and regulatory compliance. When looking to buy Diphenhydramine Hydrochloride, understanding its chemical properties and how they translate into therapeutic effects allows for more informed purchasing decisions. The CAS 147-24-0 designation serves as a universal identifier, crucial for accurate sourcing and regulatory documentation.

In essence, Diphenhydramine Hydrochloride is a multifaceted compound whose chemical properties are well-aligned with its diverse therapeutic applications. Its role in allergy management, sleep support, and motion sickness prevention highlights its importance as a pharmaceutical intermediate.