Understanding the chemical underpinnings of essential compounds like Lidocaine HCl powder is crucial for researchers, formulators, and manufacturers. This amide-type local anesthetic possesses a unique molecular structure that dictates its pharmacological properties and synthesis routes. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing not only high-purity Lidocaine HCl but also insights into its chemical nature, supporting innovation in the pharmaceutical and chemical industries.

Molecular Structure and Chemical Identity

Lidocaine HCl, chemically known as 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride, has the molecular formula C14H22N2O · HCl. Its CAS number is 6108-05-0. The hydrochloride salt form is preferred for many pharmaceutical applications because it is water-soluble, allowing for easier formulation into injectable solutions, topical gels, and creams. The molecule features a lipophilic aromatic ring connected to an intermediate amide linkage and a hydrophilic tertiary amine group. This amphipathic nature is key to its ability to penetrate cell membranes and interact with voltage-gated sodium channels. When you buy lidocaine hcl powder online, you are acquiring a compound with a well-defined chemical structure critical for its biological activity.

Synthesis of Lidocaine HCl Powder

The synthesis of Lidocaine HCl typically involves a multi-step process. A common route begins with the reaction of 2,6-dimethylaniline with chloroacetyl chloride to form 2-chloro-N-(2,6-dimethylphenyl)acetamide. This intermediate is then reacted with diethylamine to yield lidocaine base. Finally, the lidocaine base is treated with hydrochloric acid to form the desired Lidocaine HCl salt. Each step requires precise control of reaction conditions, including temperature, pressure, and reagent ratios, to ensure high purity and yield. As a leading lidocaine hcl raw powder supplier, NINGBO INNO PHARMCHEM CO.,LTD. employs advanced manufacturing processes to guarantee the quality of the synthesized Lidocaine HCl powder, adhering to strict standards like USP and BP.

Physicochemical Properties and Behavior

Lidocaine HCl powder typically appears as a white crystalline powder. It is odorless and has a bitter taste. Its solubility in water is significantly higher than that of lidocaine base, a crucial property for its use in aqueous pharmaceutical preparations. The pKa of lidocaine is around 7.7, meaning that at physiological pH, a significant portion of the molecule exists in its ionized form, which is essential for its interaction with sodium channels. Understanding these properties is vital for formulators working with lidocaine hcl pharmaceutical grade materials to achieve desired drug delivery profiles.

Applications Driven by Chemical Properties

The chemical structure and properties of Lidocaine HCl directly translate into its broad spectrum of applications. Its ability to penetrate lipid-rich nerve membranes and its interaction with sodium channels are the basis of its local anesthetic action. In its antiarrhythmic role, it affects cardiac ion channels, stabilizing the heart's electrical activity. As a lidocaine hcl chemical intermediate, its reactive functional groups allow for further chemical modifications. For companies involved in research and development, sourcing from a reliable wholesale lidocaine hcl powder manufacturer ensures access to a well-characterized compound for advanced applications.

Procurement and Supply Chain Excellence

When sourcing Lidocaine HCl, considering a partner like NINGBO INNO PHARMCHEM CO.,LTD. means prioritizing product integrity and supply chain efficiency. Our commitment to offering competitive lidocaine hydrochloride powder bulk price, coupled with expertise in lidocaine hcl powder door to door delivery and safe customs clearance lidocaine hcl, makes us an ideal partner. We ensure that the high-quality Lidocaine HCl powder you receive is produced through rigorous synthesis and purification processes, ready for your critical applications.