The Chemical Synthesis and Properties of Exenatide Acetate: A Pharmaceutical Perspective
NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing high-quality pharmaceutical ingredients, including Exenatide Acetate (CAS 141732-76-5). This section focuses on the chemical aspects of this important peptide, crucial for pharmaceutical manufacturers and researchers.
Exenatide Acetate is a synthetic peptide consisting of 39 amino acids. Its structure is derived from exendin-4, a naturally occurring hormone found in the saliva of the Gila monster. The synthesis of such a complex molecule involves sophisticated solid-phase or solution-phase peptide synthesis techniques, followed by rigorous purification processes to achieve the desired exenatide acetate purity 99%.
The chemical properties of Exenatide Acetate are critical for its biological activity. As a peptide, it is susceptible to degradation by enzymes like dipeptidyl peptidase-4 (DPP-4). However, specific modifications in its amino acid sequence, compared to native GLP-1, render it more resistant to DPP-4 degradation, thus prolonging its half-life in the body. This extended duration of action is key to its therapeutic efficacy as a GLP-1 receptor agonist.
Key chemical specifications that manufacturers look for include:
- Molecular Formula: C186H286N50O62S
- Molecular Weight: Approximately 4246.62 g/mol
- Appearance: Typically a White Lyophilized Powder
- Solubility: Soluble in water, facilitating formulation into injectable solutions.
- Purity: Ensured to be >99% via methods like High-Performance Liquid Chromatography (HPLC).
NINGBO INNO PHARMCHEM CO.,LTD. employs advanced analytical techniques such as HPLC, Nuclear Magnetic Resonance (NMR), and Mass Spectrometry (MS) to verify the identity, purity, and quality of every batch of synthetic exendin-4 peptide we produce. This commitment to quality assurance is what makes us a trusted exenatide powder supplier.
The pharmaceutical applications of Exenatide Acetate are primarily in the treatment of type 2 diabetes. Understanding the chemical stability and formulation requirements is essential for drug development. Whether it's for twice-daily injections or extended-release formulations, the quality of the raw peptide powder is paramount.
For manufacturers looking to buy exenatide CAS 141732-76-5, NINGBO INNO PHARMCHEM CO.,LTD. offers a product that meets the highest standards of chemical integrity and pharmaceutical grade quality. We ensure that our customers have access to the best price exenatide pharmaceutical grade, supporting their efforts to bring safe and effective diabetes treatments to market.
In conclusion, the chemical synthesis and precise quality control of Exenatide Acetate are fundamental to its role in modern diabetes therapy. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to upholding these standards, providing the pharmaceutical industry with a reliable source for this critical peptide.
Perspectives & Insights
Agile Reader One
“employs advanced analytical techniques such as HPLC, Nuclear Magnetic Resonance (NMR), and Mass Spectrometry (MS) to verify the identity, purity, and quality of every batch of synthetic exendin-4 peptide we produce.”
Logic Vision Labs
“This commitment to quality assurance is what makes us a trusted exenatide powder supplier.”
Molecule Origin 88
“The pharmaceutical applications of Exenatide Acetate are primarily in the treatment of type 2 diabetes.”