At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing comprehensive chemical solutions for research. This article compares 4-Amino-3-(4-fluorophenyl)butyric Acid Hydrochloride (CAS: 1858241-03-8) with other notable GABA analogs, highlighting its unique characteristics and research value.

GABA analogs are a diverse class of compounds that interact with the GABAergic system, influencing inhibitory neurotransmission in the central nervous system. Understanding these structure-activity relationships is vital for developing targeted therapeutics. Key analogs include phenibut (4-amino-3-phenylbutyric acid) and baclofen (4-amino-3-(4-chlorophenyl)butyric acid).

Compared to phenibut, 4-Amino-3-(4-fluorophenyl)butyric Acid Hydrochloride features a fluorine atom at the para position of the phenyl ring. This substitution can affect the compound's lipophilicity, electronic distribution, and metabolic stability, potentially leading to differences in receptor binding affinity and pharmacokinetic profile. While phenibut is known for its anxiolytic and nootropic effects, the fluorinated analog may offer enhanced or modulated activity. Researchers often seek to buy such derivatives to explore these nuances.

Baclofen, a well-established GABA_B receptor agonist, differs from our subject compound by having a chlorine atom instead of fluorine. Chlorine is larger and less electronegative than fluorine, which can lead to different receptor interactions. Baclofen is primarily used as a muscle relaxant due to its potent GABA_B agonism.

The specific placement and nature of substituents on the phenyl ring significantly impact the affinity and efficacy of these GABA analogs at GABA receptors. The fluorine substitution in 4-Amino-3-(4-fluorophenyl)butyric Acid Hydrochloride may contribute to improved metabolic resilience, making it a potentially valuable compound for in-depth pharmacological studies. Researchers can purchase this compound from NINGBO INNO PHARMCHEM CO.,LTD. to investigate these comparative effects.

By understanding these structural and functional differences, researchers can select the most appropriate GABA analog for their specific experimental goals. NINGBO INNO PHARMCHEM CO.,LTD. provides these critical chemical tools, supporting the scientific community's exploration into neuropharmacology and the development of new treatments for a range of conditions.