Cyclophosphamide Monohydrate: Chemical Properties, Mechanism, and Sourcing Essentials
Cyclophosphamide Monohydrate is a compound of immense significance in the pharmaceutical landscape, primarily utilized for its potent cytotoxic and immunosuppressive effects. As a key pharmaceutical raw material, its precise chemical structure and reliable sourcing are critical for drug formulation and therapeutic efficacy. This article aims to provide a detailed overview of its properties, mechanism of action, and the essential aspects of procuring it.
Chemically, Cyclophosphamide Monohydrate is characterized by its molecular formula C7H17Cl2N2O2P and a molecular weight of 279.1 g/mol. It typically presents as a white crystalline powder. Its primary function as an antineoplastic agent is attributed to its mechanism as an alkylating agent. Upon administration, it undergoes metabolic activation, primarily in the liver, to form active metabolites such as phosphoramide mustard. This active form alkylates DNA, leading to DNA strand breaks and cross-linking, thereby inhibiting DNA replication and transcription, and ultimately causing cell death. Understanding these chemical properties is fundamental for its application in cancer therapy.
The therapeutic uses of Cyclophosphamide Monohydrate are broad, encompassing the treatment of various cancers, including lymphomas, leukemias, and breast cancer. Its immunosuppressive capabilities also make it valuable in managing autoimmune diseases and in post-transplantation care. The reliability of its performance hinges on its purity and consistency, underscoring the importance of sourcing from suppliers who can guarantee these standards. For those looking to buy cyclophosphamide powder online, focusing on suppliers with strong quality control measures is essential.
NINGBO INNO PHARMCHEM CO.,LTD. serves as a reliable source for this critical pharmaceutical intermediate. By providing Cyclophosphamide Monohydrate that meets rigorous quality benchmarks, including GMP certifications, the company supports the pharmaceutical industry's demand for high-quality raw materials. Access to detailed Certificates of Analysis and assurance of consistent purity are vital when selecting a supplier.
The journey of Cyclophosphamide Monohydrate from chemical synthesis to patient treatment involves strict quality control at every step. Its role as a vital antineoplastic agent demands precision and reliability, making the selection of a trusted cyclophosphamide monohydrate manufacturer a crucial decision for any pharmaceutical company.
In essence, Cyclophosphamide Monohydrate exemplifies a critical pharmaceutical raw material whose effective use is underpinned by a deep understanding of its chemical nature and a commitment to quality sourcing. Its continued importance in treating severe medical conditions necessitates a focus on purity, compliance, and reliable supply chains.
Perspectives & Insights
Chem Catalyst Pro
“Its primary function as an antineoplastic agent is attributed to its mechanism as an alkylating agent.”
Agile Thinker 7
“Upon administration, it undergoes metabolic activation, primarily in the liver, to form active metabolites such as phosphoramide mustard.”
Logic Spark 24
“This active form alkylates DNA, leading to DNA strand breaks and cross-linking, thereby inhibiting DNA replication and transcription, and ultimately causing cell death.”