Domperidone, identified by CAS number 57808-66-9, is a chemical compound of significant value in the pharmaceutical sector, primarily serving as an Active Pharmaceutical Ingredient (API). Its well-defined chemical structure and properties enable its use in a variety of therapeutic applications, most notably as an anti-nausea and gastroprokinetic agent.

The efficacy of Domperidone stems from its action as a peripheral dopamine D2 antagonist. This pharmacological profile allows it to target specific receptors in the gastrointestinal tract and the chemoreceptor trigger zone, influencing both digestive motility and the sensation of nausea. For patients suffering from conditions like gastroparesis, where stomach emptying is delayed, Domperidone promotes rhythmic contractions of the stomach muscles, facilitating faster food transit. This makes it a crucial component in treatments aimed at improving digestive comfort and function.

As a leading Domperidone manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. ensures that the Domperidone API supplied meets rigorous quality benchmarks, often exceeding 99.5% purity. These high Domperidone purity standards are essential for its pharmaceutical applications, guaranteeing both safety and effectiveness in the final dosage forms. Customers seeking to buy Domperidone can rely on such suppliers for consistent product quality.

The compound's utility extends beyond its primary GI applications. Domperidone has also been observed to stimulate prolactin release, leading to its use in assisting with lactation. This dual-purpose application highlights the compound's versatility, although its use for lactation is often considered off-label and requires careful medical supervision.

The process of obtaining this vital API involves careful sourcing from trusted suppliers who adhere to Good Manufacturing Practices (GMP). Companies like NINGBO INNO PHARMCHEM CO.,LTD. play a crucial role in the pharmaceutical supply chain, providing the essential building blocks for medicines that improve patient outcomes. The availability of Domperidone for gastroparesis and other GI issues is critical for managing chronic and acute conditions.

In essence, Domperidone (CAS 57808-66-9) is more than just a chemical; it is a vital tool in modern medicine. Its reliable performance in treating common and debilitating GI symptoms and its potential role in supporting breastfeeding mothers make it an API of considerable importance. The commitment to quality by manufacturers ensures that this compound continues to be a cornerstone in pharmaceutical development and patient care.