Lipidomics, the large-scale study of lipids, is a rapidly advancing field that offers profound insights into cellular function, disease mechanisms, and therapeutic targets. At the heart of many lipidomic studies are model lipid systems, which allow for the controlled investigation of lipid behavior and interactions. 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC), CAS 4235-95-4, is a workhorse phospholipid in this domain, prized for its well-defined structure and biophysical properties.

DOPC, a major component of biological membranes, is synthesized with unsaturated oleic acid chains, contributing to its high fluidity. This characteristic makes it an excellent choice for creating model membranes, such as giant unilamellar vesicles (GUVs) or supported lipid bilayers, that closely mimic the dynamic environment of cellular plasma membranes. Researchers use DOPC to construct these models to study how various cellular components, including proteins, peptides, and other lipids, interact with and influence membrane structure and dynamics. The ability to buy phospholipid online with precise specifications is crucial for replicating complex biological systems in vitro.

In lipidomics, DOPC is often used as a reference lipid or as a primary component in lipid mixtures. Its predictable behavior under different conditions allows researchers to calibrate analytical instruments, validate experimental protocols, and understand the baseline properties of membrane systems before introducing more complex variables. The high purity of DOPC (typically >98%) is essential for accurate quantitative analysis and the precise interpretation of lipidomic data.

Furthermore, DOPC's role in drug delivery research, particularly in the context of liposomes and lipid nanoparticles, directly impacts lipidomic studies. Understanding how drug formulations containing DOPC interact with cellular lipids can reveal new insights into drug efficacy and side effects. The research into 1,2-Dioleoyl-sn-glycero-3-phosphocholine applications in drug delivery provides a bridge between lipid behavior and therapeutic outcomes.

For lipidomic scientists, sourcing high-quality DOPC is critical. Access to reliable suppliers offering high purity DOPC ensures the integrity of experiments. The continued exploration of 18:1 cis PC properties and its interactions within complex lipid environments promises to further illuminate the intricate world of cellular lipids and their physiological roles.

In essence, 1,2-Dioleoyl-sn-glycero-3-phosphocholine is an indispensable tool in lipidomic research, enabling the creation of relevant model systems and providing a benchmark for understanding the complex behavior of cellular lipids. Its contributions are vital for advancing our knowledge of cellular biology and developing novel therapeutic strategies.