Lafutidine, identified by its CAS number 118288-08-7, is a significant compound within the pharmaceutical industry, primarily recognized for its role as an effective histamine H2 receptor antagonist. A deep dive into its chemical properties and applications reveals why it is a critical component in managing various gastrointestinal disorders.

Chemically, Lafutidine (MF C22H29N3O4S, MW 431.55) is a white powder with a melting point between 92.7-94.9°C. Its structure and properties lend themselves to its pharmacological activity, including rapid absorption and a relatively long half-life that ensures sustained therapeutic effects. These characteristics are vital for its primary function in inhibiting gastric acid secretion. The molecule’s specific composition allows it to effectively bind to H2 receptors on gastric parietal cells.

The main application of Lafutidine is in the pharmaceutical sector, where it is a key active pharmaceutical ingredient (API) for medications treating peptic ulcers and GERD. Its dual action of potent acid inhibition and gastroprotection makes it a preferred choice over many other treatments. The ability to buy Lafutidine in bulk from specialized suppliers supports its widespread use in manufacturing these essential medications.

Beyond its direct use in finished pharmaceutical products, Lafutidine also plays a role as a fine chemical intermediate. Its complex organic structure can serve as a building block or starting material in the synthesis of other specialized chemical compounds, although its primary market remains pharmaceutical applications. The rigorous quality standards, such as GMP and USP certifications, associated with Lafutidine production underscore its importance as a high-grade pharmaceutical chemical.

The Lafutidine mechanism of action, which involves both acid suppression and mucosal defense enhancement, is a testament to sophisticated drug design. By understanding Lafutidine uses and its chemical profile, researchers and manufacturers can continue to leverage its benefits for improved patient outcomes. Ensuring a reliable supply of high-quality Lafutidine powder is crucial for the continuous production of effective gastrointestinal treatments.