The study of cellular membranes is fundamental to understanding a myriad of biological processes. Artificial membrane models, often constructed using phospholipids, provide researchers with controlled environments to investigate these complex phenomena. Among the most widely utilized phospholipids for this purpose is 1,2-Dioleoyl-sn-glycero-3-phosphocholine, commonly known as DOPC (CAS 4235-95-4). Its unique properties make it an invaluable tool for biophysical research.

DOPC is a zwitterionic phospholipid characterized by its two oleoyl chains, unsaturated fatty acids that impart significant fluidity to lipid bilayers. This fluidity is crucial for mimicking the dynamic nature of biological membranes, allowing for accurate studies of membrane protein interactions, lipid domain formation, and membrane fusion events. The low phase transition temperature of DOPC, typically around -17°C, ensures it remains in a liquid-crystalline state across a wide range of physiological temperatures, a key factor when aiming to buy phospholipid online for membrane research.

Researchers employ DOPC in the formation of various artificial membrane structures, including liposomes, vesicles, and supported lipid bilayers. These models are instrumental in exploring fundamental biophysical questions, such as how membrane composition influences permeability, how different molecules partition into specific membrane domains, and the mechanisms by which drugs or toxins interact with cell surfaces. The consistent quality and high purity, often exceeding 98%, of DOPC are essential for obtaining reproducible and reliable experimental data in these sensitive studies.

The application of DOPC extends to understanding the mechanisms of drug action. For instance, its role in liposomal drug delivery systems is well-documented, where it contributes to the stability and targeted release of therapeutic agents. The insights gained from 1,2-Dioleoyl-sn-glycero-3-phosphocholine applications in membrane research often directly translate into improved drug design and delivery strategies.

In summary, DOPC is a cornerstone phospholipid for anyone engaged in biophysical membrane studies. Its inherent fluidity, biocompatibility, and utility in forming diverse membrane structures make it an indispensable component for advancing our understanding of cellular membranes and developing novel therapeutic interventions. When sourcing materials for such research, understanding the market for high purity DOPC and the specific uses of 18:1 cis PC is paramount for success.