NINGBO INNO PHARMCHEM CO.,LTD. offers an in-depth exploration of Fosfomycin Disodium Salt (CAS 26016-99-9), focusing on its intrinsic chemical characteristics and its sophisticated antibacterial mechanism. This compound is a testament to targeted drug design in combating bacterial threats.

Chemically, Fosfomycin Disodium Salt presents as a white crystalline powder. Its molecular formula is C3H5Na2O4P, with a molecular weight of approximately 182.02 g/mol. A key physical property is its high solubility in water, which facilitates its preparation and application in both laboratory settings and clinical formulations. This solubility is critical for its bioavailability and distribution within the body or in culture media.

The primary mechanism by which Fosfomycin Disodium Salt exerts its antibacterial effect is through the irreversible inhibition of the MurA enzyme. This enzyme is a pivotal player in the bacterial cell wall biosynthesis pathway, specifically catalyzing the transfer of enolpyruvate to UDP-N-acetylglucosamine (UDP-GlcNAc). By blocking this reaction, Fosfomycin disrupts the production of N-acetylmuramic acid (NAM), a fundamental building block of peptidoglycan. This disruption ultimately compromises the integrity of the bacterial cell wall, leading to cell lysis and death. This makes it an excellent example of a bacterial cell wall synthesis inhibitor.

This specific mode of action provides Fosfomycin Disodium Salt with a broad spectrum of activity, effectively targeting numerous Gram-positive and Gram-negative bacteria. Notably, its efficacy against certain multidrug-resistant pathogens makes it a valuable asset in the face of growing antibiotic resistance. Researchers are keenly interested in its antibacterial activity against drug-resistant strains to understand how to best utilize and potentially enhance its effectiveness.

The compound's utility as a pharmaceutical chemical is further underscored by its application in treating conditions like urinary tract infections. Its pharmacokinetic profile, including good absorption and concentration in the urinary tract, contributes to its therapeutic success. For healthcare providers and researchers, understanding the precise chemical properties and reaction kinetics is essential when considering the purchase of Fosfomycin Disodium Salt.

Moreover, its role as a MurA enzyme inhibitor pharmaceutical is a focus for academic and industrial research. Studies aim to elucidate the precise binding interactions and conformational changes induced by Fosfomycin Disodium Salt on the MurA enzyme. Such detailed investigations are fundamental to the discovery of new antibacterial agents that exploit similar pathways.

In summary, Fosfomycin Disodium Salt is a compound of significant chemical and biological interest. Its well-defined crystalline structure, water solubility, and highly specific inhibitory action on bacterial MurA enzyme position it as a critical antibiotic. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing this high-quality compound, enabling critical research and therapeutic applications that combat bacterial infections effectively.