At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing researchers with high-quality chemical compounds. Nicotinamide (CAS 98-92-0), a vital B vitamin derivative, possesses a unique set of chemical properties that underpin its diverse applications in biochemical research.

Nicotinamide is a water-soluble compound, exhibiting significant solubility in water (up to 1000 g/L at 20°C), as well as in ethanol, glycerol, and DMSO. This high solubility is advantageous for its formulation in various aqueous solutions used in laboratory settings. It typically appears as a white crystalline powder or colorless crystals, with a melting point generally ranging from 128-131°C. These physical characteristics are crucial for identification and quality control in research and development.

The biochemical significance of Nicotinamide cannot be overstated. It is a fundamental component of the coenzymes NAD+ and NADP+, which are essential for a vast array of redox reactions in living organisms. These coenzymes are critical for cellular energy production, DNA repair, and cellular signaling pathways. Researchers utilize Nicotinamide to study these vital processes, investigating how NAD+ levels influence cellular function, metabolism, and the aging process.

Furthermore, Nicotinamide is known to inhibit certain enzymes, such as poly(ADP-ribose) polymerases (PARPs). PARPs are involved in DNA repair mechanisms, and understanding Nicotinamide's inhibitory effect on these enzymes provides insights into therapeutic strategies for diseases like cancer. Its role in regulating sirtuins, a family of NAD+-dependent enzymes linked to longevity and gene expression, also makes it a compound of intense research interest.

The exploration of Nicotinamide's chemical properties and its intricate biochemical roles continues to reveal new research possibilities. NINGBO INNO PHARMCHEM CO.,LTD. provides researchers with reliable, high-purity Nicotinamide, supporting advancements in fields ranging from molecular biology to medicine. Investigate the scientific potential of Nicotinamide for your next research project.