Phenylbutazone, identified by its CAS number 50-33-9, is a complex organic compound with significant pharmacological activity. As a non-steroidal anti-inflammatory drug (NSAID), its chemical structure dictates its mechanism of action and therapeutic applications. Chemically, Phenylbutazone is a pyrazolone derivative, specifically 4-butyl-1,2-diphenylpyrazolidine-3,5-dione. This molecular framework is responsible for its ability to inhibit prostaglandin synthesis, a key process in inflammation and pain signaling.

A thorough Phenylbutazone chemical properties analysis reveals a white to off-white crystalline powder. It is sparingly soluble in water but more soluble in organic solvents like ethanol and acetone. The compound's stability and reactivity are critical factors for manufacturers and researchers. Understanding its synthesis involves multi-step organic reactions, typically starting with precursors that form the pyrazolidine ring structure, followed by alkylation and aryl substitutions. The availability of Phenylbutazone API suppliers in China ensures that these complex manufacturing processes are carried out to meet global demand.

The Phenylbutazone history medical context highlights the initial excitement surrounding its development, driven by its potent anti-inflammatory effects. Early research focused on understanding its pharmacokinetics, including absorption, distribution, metabolism, and excretion. Phenylbutazone is extensively metabolized in the liver, producing several active metabolites, such as oxyphenbutazone. The variations in metabolism and clearance rates across different species, particularly the significantly slower clearance in humans compared to horses, have been central to its divergent regulatory fates. This disparity underscores the importance of Phenylbutazone CAS 50-33-9 uses and safety profiles being species-specific.

For laboratories and chemical manufacturers, rigorous quality control and analytical methods are essential when dealing with Phenylbutazone. Techniques such as High-Performance Liquid Chromatography (HPLC) are commonly employed to determine purity and quantify related substances. The detailed Phenylbutazone chemical properties analysis provided in scientific literature guides its proper handling, storage, and formulation, ensuring its therapeutic potential is realized safely and effectively, especially when considering where to buy Phenylbutazone powder.