At NINGBO INNO PHARMCHEM CO.,LTD., we appreciate the foundational role that detailed chemical understanding plays in pharmaceutical advancement. Trabectedin, a significant API (CAS 114899-77-3), is characterized by a complex structure and specific properties that dictate its potent antineoplastic activity.

Trabectedin is a macrocyclic compound belonging to the tetrahydroisoquinoline alkaloid family. Its intricate molecular structure, C39H43N3O11S, features multiple fused rings and chiral centers, contributing to its precise interaction with DNA. The compound's physical properties, such as its solid form and light yellow to yellow color, are important for identification and quality control. Its solubility in solvents like methanol and chloroform also influences its formulation and handling.

The primary application of Trabectedin lies in its use as an anticancer agent. Its mechanism involves binding to the minor groove of DNA and alkylating guanine residues, leading to DNA bending and interference with cellular processes like transcription and DNA repair. This action is particularly effective against cancer cells and is the basis for its use in treating advanced soft tissue sarcoma and certain types of ovarian cancer. Understanding these Trabectedin properties is crucial for its successful integration into therapeutic regimens.

For pharmaceutical manufacturers, the consistent availability of Trabectedin powder with defined purity is essential. NINGBO INNO PHARMCHEM CO.,LTD. serves as a reliable source for this vital compound, ensuring that it meets the stringent specifications required for pharmaceutical applications. The rigorous quality checks performed on Trabectedin API suppliers ensure that the chemical profile remains consistent and reliable for downstream processes.

The ongoing research into the pharmacological aspects of Trabectedin, including its ADMET properties and potential drug interactions, further underscores the importance of its detailed chemical profile. As we continue to support the pharmaceutical industry, NINGBO INNO PHARMCHEM CO.,LTD. remains committed to providing essential APIs like Trabectedin, facilitating advancements in cancer treatment.