The Chemistry and Pharmacology of Lidocaine Powder (CAS 137-58-6)
Lidocaine, chemically known by its CAS number 137-58-6, is an amide-type local anesthetic and antiarrhythmic drug that plays a pivotal role in numerous medical treatments. At NINGBO INNO PHARMCHEM CO.,LTD., we offer high-purity lidocaine powder, understanding its complex chemical makeup and critical pharmacological functions.
The chemical structure of lidocaine features a lipophilic aromatic ring and a hydrophilic amine group, linked by an amide bond. This amphipathic nature is key to its ability to penetrate nerve cell membranes and block voltage-gated sodium channels. The powder form, typically white and crystalline, is the precursor to various pharmaceutical formulations, including solutions, creams, and patches. The meticulous manufacturing process ensures a high purity, often exceeding 99%, which is vital for its medicinal applications.
Pharmacologically, lidocaine's primary mechanism of action involves the reversible blockade of nerve conduction. By binding to the intracellular side of voltage-gated sodium channels, it inhibits the influx of sodium ions, which is essential for action potential generation and propagation. This effect leads to local anesthesia, preventing the transmission of pain signals from peripheral nerves to the central nervous system. For healthcare professionals seeking reliable lidocaine powder, NINGBO INNO PHARMCHEM CO.,LTD. ensures consistent quality and availability.
Furthermore, lidocaine's antiarrhythmic properties are also attributed to its action on sodium channels, particularly in cardiac tissue. It shortens the action potential duration and reduces the effective refractory period of the ventricles, making it effective in treating ventricular tachyarrhythmias. The precise control over sodium channel activity makes it a valuable therapeutic agent. Sourcing this compound from a reputable lidocaine powder manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. guarantees that its chemical integrity and pharmacological potency are maintained, supporting advancements in both pain management and cardiac care.
Perspectives & Insights
Silicon Analyst 88
“The meticulous manufacturing process ensures a high purity, often exceeding 99%, which is vital for its medicinal applications.”
Quantum Seeker Pro
“Pharmacologically, lidocaine's primary mechanism of action involves the reversible blockade of nerve conduction.”
Bio Reader 7
“By binding to the intracellular side of voltage-gated sodium channels, it inhibits the influx of sodium ions, which is essential for action potential generation and propagation.”