NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing essential pharmaceutical ingredients, and understanding the chemistry behind these compounds is central to our mission. Vildagliptin, a vital DPP-4 inhibitor for type 2 diabetes, possesses a unique molecular structure and specific chemical properties that dictate its synthesis and efficacy.

Vildagliptin, chemically known as (2S)-1-[2-[(3-hydroxytricyclo[3.3.1.1[3,7]]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile, has the molecular formula C17H25N3O2 and a molecular weight of approximately 303.40 g/mol. Its structure features a pyrrolidine ring with a nitrile group, linked via an acetyl moiety to a 3-hydroxyadamantyl group. This complex arrangement is crucial for its high affinity and selectivity for the DPP-4 enzyme.

The synthesis of Vildagliptin involves multi-step chemical processes. While specific proprietary methods vary among manufacturers, typical synthetic routes often involve the coupling of a protected 2-cyanopyrrolidine derivative with an appropriately functionalized adamantane amine precursor. Key steps include forming the amide bond and deprotection strategies to yield the final active pharmaceutical ingredient. Ensuring the correct stereochemistry, particularly the (S)-configuration at the pyrrolidine ring, is critical for optimal biological activity. The 'Vildagliptin synthesis' process requires precise control over reaction conditions and purification techniques.

Physically, Vildagliptin is typically described as a white to off-white crystalline powder. Its melting point is generally reported in the range of 149-155°C. Solubility characteristics are also important; Vildagliptin may be soluble in organic solvents such as DMSO or ethanol, and it has limited solubility in water, which influences its formulation and bioavailability. For 'Vildagliptin API' intended for pharmaceutical use, these physical and chemical properties are rigorously controlled and documented.

As a Vildagliptin manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. adheres to strict quality control measures throughout the synthesis process. This ensures that the Vildagliptin we supply meets the high standards required for pharmaceutical applications, contributing to the reliable treatment of type 2 diabetes. Understanding the 'Vildagliptin properties' is essential for formulators and researchers alike. The 'Vildagliptin price' reflects the complexity of its synthesis and the stringent quality assurance involved.

Our commitment to chemical excellence ensures that our Vildagliptin is of the highest purity and consistency, supporting the global effort to combat type 2 diabetes through effective pharmaceutical solutions.