In the realm of pharmaceuticals and medical research, certain compounds stand out for their multifaceted applications and profound impact. Phentolamine Mesylate, identified by its CAS number 65-28-1, is one such compound. As a synthetic imidazoline derivative, it functions as a potent non-selective alpha-adrenergic antagonist. This fundamental property underpins its therapeutic utility and its extensive use in scientific investigations. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Phentolamine Mesylate to support advancements in these critical fields.

The pharmacological action of Phentolamine Mesylate is primarily its ability to competitively block alpha-1 and alpha-2 adrenergic receptors. This blockade leads to vasodilation, a widening of blood vessels, which in turn reduces peripheral vascular resistance and lowers blood pressure. This mechanism of action makes Phentolamine Mesylate an indispensable agent in the management of hypertension and hypertensive emergencies. Clinicians rely on its effectiveness to stabilize patients experiencing dangerously high blood pressure, often associated with conditions like pheochromocytoma.

Pheochromocytoma, a tumor of the adrenal gland that secretes catecholamines, causes severe hypertension. Phentolamine Mesylate is crucial both in managing the associated hypertensive crises and in its preoperative preparation to prevent intraoperative blood pressure surges. The precise control it offers is vital for patient safety during surgical interventions.

Beyond its direct therapeutic uses, Phentolamine Mesylate serves as a valuable research chemical. Scientists utilize it to study the intricate workings of the adrenergic system, investigate new drug targets, and understand the physiological responses mediated by alpha-adrenergic receptors. The availability of high-purity Phentolamine Mesylate, such as that offered for purchase by NINGBO INNO PHARMCHEM CO.,LTD., is paramount for obtaining reliable and reproducible experimental outcomes. When sourcing Phentolamine Mesylate, considering its purity and supplier reputation is essential for your research needs.

The compound’s solubility in water and ethanol, along with its appearance as a white to off-white crystalline powder, are important physical characteristics for its formulation and handling. Researchers investigating cardiovascular diseases or developing novel treatments for conditions involving vascular tone often seek reliable suppliers for Phentolamine Mesylate to buy. Factors such as competitive pricing and secure shipping are also considered by institutions and laboratories procuring these essential materials.

In summary, Phentolamine Mesylate is more than just a chemical compound; it is a critical therapeutic and research tool. Its role in cardiovascular medicine, particularly in managing hypertension and pheochromocytoma, is well-established. As a research chemical, it continues to facilitate groundbreaking discoveries in pharmacology. NINGBO INNO PHARMCHEM CO.,LTD. is proud to contribute to these advancements by supplying top-tier Phentolamine Mesylate, supporting the global scientific and medical communities.