NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide a comprehensive overview of Spectinomycin Dihydrochloride API, a critical antibiotic with diverse applications in pharmaceutical and veterinary fields. This article delves into its core value, mechanism of action, and the distinct advantages it offers to healthcare professionals and animal husbandry experts alike.

Spectinomycin dihydrochloride pentahydrate, a unique aminoglycoside antibiotic derived from Streptomyces spectabilis, plays a significant role in combating bacterial infections. Its primary mechanism involves interfering with bacterial protein synthesis by binding to the 30S subunit of ribosomes, a process that ultimately leads to bacterial cell death. This concentration-dependent antibiotic action makes it particularly effective against static bacteria.

The antibacterial spectrum of Spectinomycin Dihydrochloride API is notable for its high sensitivity towards Neisseria gonorrhoeae, including strains resistant to beta-lactam antibiotics. It also shows efficacy against Mycoplasma urealyticum, which is relevant for reproductive system infections. Moderately sensitive bacteria include certain Enterobacteriaceae, such as Escherichia coli and Salmonella. However, it's important to note that bacteria like Pseudomonas aeruginosa typically exhibit resistance, and it is not active against Chlamydia trachomatis or Treponema pallidum.

In human medicine, Spectinomycin Dihydrochloride API is recognized for its role as a second-line treatment for gonorrhea, especially in cases of penicillin and tetracycline resistance. It is commonly used for urethritis, cervicitis, and proctitis, with recommended dosages for intramuscular injection. Given the frequent co-infection with Chlamydia trachomatis, combination therapy with other antibiotics like tetracycline, doxycycline, or erythromycin is often advised for a comprehensive treatment approach. The low nephrotoxicity of Spectinomycin Dihydrochloride API, especially when compared to other aminoglycosides, coupled with its convenient single-dose administration, continues to make it a valuable option in clinical practice.

Beyond human health, Spectinomycin Dihydrochloride API finds substantial application in veterinary medicine. It is effective in treating infections in livestock and poultry caused by pathogens such as Escherichia coli, Salmonella, Pasteurella, and Mycoplasma. A notable advantage is its synergistic effect when combined with lincomycin in a 2:1 ratio, enhancing the antibacterial spectrum and proving effective against pig dysentery and chronic respiratory diseases in poultry. Its utility also extends to aquaculture, where it is used for the prevention and treatment of bacterial enteritis and streptococcal diseases in fish, administered orally or via medicinal baths. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-quality Spectinomycin Dihydrochloride API to meet these critical health needs.