Understanding the Specifications and Purity of DOPC for Scientific Research
In scientific research, particularly in fields involving biomolecular interactions and advanced materials, the quality and purity of reagents are paramount. 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC), CAS 4235-95-4, is a widely used phospholipid, and understanding its specifications and purity is crucial for obtaining accurate and reproducible results. As a key component in liposomes, artificial membranes, and drug delivery systems, the precise characteristics of DOPC directly influence experimental outcomes.
DOPC, chemically known as C44H84NO8P, is a zwitterionic phospholipid with a molecular weight of approximately 786.11 g/mol. Its structure features two oleoyl chains, unsaturated fatty acids that contribute to its characteristic fluidity. This unsaturation is key to its functionality in biological mimicry, allowing membranes to remain in a liquid-crystalline state at physiological temperatures. When researchers decide to buy phospholipid online, they look for these precise specifications to match their experimental needs.
Purity is a critical parameter for DOPC used in scientific applications. High purity, typically greater than 98% or even 99%, ensures that experimental results are attributable to the intended molecule and not to contaminants. Impurities could interfere with membrane formation, alter fluidity, or lead to unpredictable interactions, compromising the validity of research findings. Therefore, sourcing DOPC from reputable manufacturers who provide detailed Certificates of Analysis (CoA) is essential.
The applications of DOPC are diverse, ranging from fundamental biophysical studies of membrane behavior to the development of sophisticated drug delivery systems, including lipid nanoparticles for mRNA vaccines. In each of these areas, the specified properties of DOPC, such as its assay percentage, absence of degradation products, and consistent fatty acid composition (18:1 (Δ9-Cis) PC), are vital. Understanding these 1,2-Dioleoyl-sn-glycero-3-phosphocholine applications helps researchers select the appropriate grade of the material.
For scientists and pharmaceutical developers, ensuring access to reliable sources for high purity DOPC is a strategic consideration. Whether for creating model membranes in biophysics labs or formulating advanced therapeutics, the quality of DOPC directly impacts success. The market for 18:1 cis PC is competitive, with many suppliers offering various grades, emphasizing the need for careful selection.
In summary, the specifications and purity of 1,2-Dioleoyl-sn-glycero-3-phosphocholine are critical determinants of its performance in scientific research and pharmaceutical development. Adhering to high standards in sourcing and application ensures the integrity of experiments and the efficacy of developed technologies.
Perspectives & Insights
Silicon Analyst 88
“In each of these areas, the specified properties of DOPC, such as its assay percentage, absence of degradation products, and consistent fatty acid composition (18:1 (Δ9-Cis) PC), are vital.”
Quantum Seeker Pro
“Understanding these 1,2-Dioleoyl-sn-glycero-3-phosphocholine applications helps researchers select the appropriate grade of the material.”
Bio Reader 7
“For scientists and pharmaceutical developers, ensuring access to reliable sources for high purity DOPC is a strategic consideration.”