Ursodeoxycholic Acid (UDCA) in Focus: Chemical Properties and Pharmaceutical Uses
Ursodeoxycholic Acid (UDCA), identified by CAS 128-13-2, is a bile acid renowned for its unique chemical properties and extensive pharmaceutical applications. Ningbo Inno Pharmchem Co., Ltd. delves into the science behind this compound, highlighting its structure, functions, and critical role in healthcare.
Chemically, UDCA is a dihydroxycholanoic acid, with specific stereochemistry that renders it hydrophilic. This hydrophilic nature is fundamental to its therapeutic actions. Unlike more hydrophobic bile acids, UDCA interacts differently with bile components and cell membranes. It integrates into bile salt micelles, increasing the bile's capacity to solubilize cholesterol and reducing the lithogenicity of bile. This property is directly leveraged in the ursodeoxycholic acid gallstone treatment, where it promotes the dissolution of cholesterol gallstones.
The pharmaceutical utility of UDCA extends significantly to liver protection and the management of cholestatic liver diseases. UDCA is a primary therapeutic agent for Primary Biliary Cirrhosis (PBC) and is also used in treating chronic hepatitis and bile reflux gastritis. Its mechanism involves protecting liver cells (hepatocytes) from damage induced by toxic bile acids, modulating immune responses within the liver, and improving bile flow. The consistent demand for udca powder benefits reflects its efficacy in these conditions.
As a high-purity chemical, UDCA serves as a crucial pharmaceutical intermediate. When professionals decide to buy ursodeoxycholic acid powder online, they are often seeking a reliable building block for drug synthesis or formulation. The quality of this intermediate directly impacts the final drug product's safety and efficacy.
Understanding the ursodeoxycholic acid chemical properties, such as its molecular weight (392.57 g/mol) and its solubility characteristics, is essential for its appropriate handling and application in pharmaceutical manufacturing. Its crystalline powder form, typically white or off-white, meets the stringent appearance standards required for active pharmaceutical ingredients (APIs).
Ningbo Inno Pharmchem Co., Ltd. is committed to providing pharmaceutical-grade UDCA that meets rigorous quality specifications. By understanding and adhering to the precise chemical properties and therapeutic applications of UDCA, we ensure our clients receive a product that contributes to successful pharmaceutical outcomes and improved patient health.
Perspectives & Insights
Nano Explorer 01
“Understanding the ursodeoxycholic acid chemical properties, such as its molecular weight (392.”
Data Catalyst One
“57 g/mol) and its solubility characteristics, is essential for its appropriate handling and application in pharmaceutical manufacturing.”
Chem Thinker Labs
“Its crystalline powder form, typically white or off-white, meets the stringent appearance standards required for active pharmaceutical ingredients (APIs).”