At NINGBO INNO PHARMCHEM CO.,LTD., we pride ourselves on providing detailed insights into the chemical compounds that drive scientific advancement. Vandetanib, known by its CAS number 443913-73-3, stands out as a critical research chemical with profound therapeutic implications. This article delves into the specifics of its chemical profile and its expanding role in targeted therapy and broader pharmaceutical research. Examining the Vandetanib chemical properties is the first step to appreciating its versatility.

Vandetanib presents as a white crystalline powder, a characteristic that facilitates its handling and use in laboratory settings. Its purity typically exceeds 98%, ensuring the reliability of experimental results. A key attribute is its solubility, particularly in DMSO, which is vital for preparing concentrated stock solutions used in various in vitro assays. This solubility profile makes it an accessible compound for researchers exploring its various biological activities, thus supporting extensive Vandetanib research efforts.

The therapeutic significance of Vandetanib is deeply rooted in its action as a multi-targeted tyrosine kinase inhibitor. It is recognized for its potent inhibition of RET, vascular endothelial growth factor receptor (VEGFR), and epidermal growth factor receptor (EGFR). These kinases play pivotal roles in the development and progression of various cancers. Understanding the nuances of the Vandetanib mechanism of action is essential for researchers aiming to develop next-generation therapeutics. Its ability to disrupt these signalling pathways makes it a cornerstone in the study of targeted cancer treatments.

The compound's journey in the pharmaceutical landscape includes its notable approval for late-stage medullary thyroid cancer, a testament to its efficacy. The specific focus on Vandetanib for medullary thyroid cancer has paved the way for further investigations into its potential against other forms of cancer, including non-small-cell lung cancer. This broad applicability highlights why Vandetanib is a sought-after compound in drug discovery chemical libraries, providing a robust foundation for screening and development.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to ensuring that scientists have access to the highest quality research materials. Our supply of Vandetanib facilitates exploration into the frontiers of targeted therapy and cancer treatment. By understanding and utilizing the unique characteristics of Vandetanib, researchers can continue to make breakthroughs in drug development, advancing the fight against cancer and improving patient outcomes worldwide.