Ningbo Innopharmachem Co., Ltd. supplies a wide range of chemical compounds, and Rafoxanide stands out due to its fascinating chemical structure and its broad spectrum of applications. While initially celebrated for its efficacy in veterinary medicine, recent scientific discoveries are highlighting its potential in innovative research areas, particularly in oncology.

Rafoxanide, a halogenated salicylanilide, possesses a unique molecular structure that underpins its biological activity. Its chemical formula, C19H11Cl2I2NO3, and CAS number 22662-39-1, denote a complex molecule designed to interfere with vital biological processes. In its primary veterinary application, Rafoxanide acts as an uncoupler of oxidative phosphorylation in parasites. This biochemical action disrupts the energy production machinery within organisms like liver flukes and nematodes, leading to their demise. This mechanism is well-documented and crucial for its effectiveness in livestock health.

The versatility of Rafoxanide extends into cutting-edge cancer research. Scientists are investigating its potential to combat various forms of cancer, including non-small cell lung cancer (NSCLC). The research indicates that Rafoxanide can inhibit cancer cell proliferation and migration by inducing cellular stress, specifically endoplasmic reticulum (ER) stress. This stress response can lead to programmed cell death (apoptosis) in cancer cells, offering a novel therapeutic strategy.

Moreover, Rafoxanide is being explored for its role in modulating cellular pathways that are critical in cancer development and progression, such as the unfolded protein response (UPR) and cell cycle regulation. Its ability to inhibit certain kinases, like CDK4/6, further positions it as a compound with significant therapeutic promise in human medicine.

The exploration of Rafoxanide showcases the power of chemical compounds to serve multiple biological functions. From safeguarding animal health to potentially treating life-threatening human diseases, its chemistry is truly remarkable. Ningbo Innopharmachem Co., Ltd. is committed to providing researchers with access to high-quality Rafoxanide, supporting the ongoing scientific exploration of its diverse applications and contributing to advancements in both veterinary science and human therapeutics.