Vidarabine, known by its CAS number 5536-17-4, is a fascinating molecule with a distinct set of chemical properties that underpin its utility in both research and pharmaceutical applications. As a nucleoside analog, its structure—an arabinose sugar linked to adenine—distinguishes it from natural nucleosides and dictates its biological behavior.

Chemically, Vidarabine typically presents as a white to off-white crystalline powder. Key properties include a melting point around 257-265 °C (with decomposition), indicating its thermal stability within a certain range. Its solubility profile is notable: it is soluble in polar organic solvents like DMF and DMSO, and moderately soluble in water, which is crucial for formulation and experimental use. These specific characteristics are vital for researchers and manufacturers when handling and processing the compound.

The synthesis of Vidarabine has been achieved through both microbiological fermentation and chemical routes. Microbiological methods, often utilizing strains of *Streptomyces antibioticus*, have been a traditional source. Chemically, its synthesis involves complex multi-step processes, often starting from protected sugar derivatives and purine bases, demonstrating significant advancements in organic synthesis. The precise control over these synthesis pathways ensures the high purity required for pharmaceutical applications.

The importance of Vidarabine extends to its role as a pharmaceutical intermediate. Its structure serves as a scaffold for creating more complex antiviral agents. For instance, research into prodrugs or modified nucleosides that improve oral bioavailability or target specific viral enzymes often starts with Vidarabine. This makes the reliable supply of Vidarabine crucial for drug discovery and development pipelines.

NINGBO INNO PHARMCHEM CO.,LTD. contributes significantly by providing high-quality Vidarabine, supporting these complex synthesis requirements. Their commitment ensures that researchers and developers have access to a reliable source for this critical chemical intermediate, facilitating advancements in antiviral therapies and other related research fields.

In essence, understanding the chemical properties and synthesis of Vidarabine is fundamental to appreciating its value in the scientific and pharmaceutical industries.