At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing high-quality pharmaceutical intermediates, and Aprepitant (CAS No. 290297-26-6) is a prime example of our expertise. This article offers an in-depth look at the chemistry behind Aprepitant, detailing its synthesis, molecular characteristics, and physical properties, all crucial for its application in advanced pharmaceuticals.

The Aprepitant chemical structure is complex, featuring a chiral center and multiple functional groups, including trifluoromethyl and fluoro-phenyl moieties. Its IUPAC name is 5-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one, and its molecular formula is C23H21F7N4O3. The molecular weight is approximately 534.4 g/mol. The synthesis of Aprepitant involves sophisticated organic chemistry techniques to achieve the correct stereochemistry and high purity required for pharmaceutical use. This process is a critical aspect of the Aprepitant drug synthesis.

Physically, Aprepitant is typically presented as a White Crystalline Powder. Its properties, such as solubility and stability, are carefully controlled during manufacturing to ensure optimal performance in its intended applications. The rigorous Aprepitant quality control measures employed by NINGBO INNO PHARMCHEM CO.,LTD. ensure that each batch of this Aprepitant pharmaceutical intermediate meets stringent specifications.

The primary application of Aprepitant is as an antiemetic, specifically targeting nausea and vomiting associated with chemotherapy and surgery. Its mechanism of action as an NK1 receptor antagonist is a direct result of its unique chemical structure, which allows for precise interaction with biological targets. The development and production of such complex molecules underscore the importance of advanced chemical synthesis capabilities within the pharmaceutical industry.

For companies looking to source Aprepitant, understanding its chemical profile is essential for successful formulation and regulatory compliance. NINGBO INNO PHARMCHEM CO.,LTD. provides comprehensive data on Aprepitant properties, ensuring transparency and facilitating the procurement process. Whether for research or large-scale manufacturing, our commitment to quality makes us a reliable partner. We make it easy to buy Aprepitant, supporting the entire Aprepitant supply chain.

In summary, the chemistry of Aprepitant is a testament to modern pharmaceutical innovation. Its complex synthesis and specific properties are critical for its role as a potent antiemetic. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to advancing healthcare by supplying high-quality Aprepitant pharmaceutical intermediates, contributing to the development of life-enhancing medications.