Vidarabine (CAS 5536-17-4) in Focus: Understanding its Impact on Viral DNA Polymerase
Vidarabine, identified by its CAS number 5536-17-4, is a molecule of significant interest in virology due to its potent antiviral capabilities. Central to its efficacy is its role as a vidarabine DNA polymerase inhibitor, a mechanism that directly targets the replication machinery of various viruses, particularly herpes simplex virus (HSV) and varicella zoster virus (VZV).
The mechanism of action for Vidarabine is complex and highly specific. Once administered, Vidarabine is converted intracellularly into its active triphosphate form, vidarabine triphosphate. This active metabolite then competes with the natural substrate, deoxyadenosine triphosphate (dATP), for incorporation into the growing viral DNA chain by viral DNA polymerase. Critically, vidarabine triphosphate also acts as a chain terminator, prematurely halting viral DNA synthesis. This dual action effectively cripples the virus's ability to replicate.
This precise interaction with viral DNA polymerase makes Vidarabine a valuable tool for researchers studying viral replication pathways. By understanding how Vidarabine inhibits this essential enzyme, scientists can gain deeper insights into the vulnerabilities of viruses and design more effective antiviral drugs. The ongoing exploration of the vidarabine antiviral mechanism contributes to a broader understanding of nucleoside analog therapies.
The availability of high-quality Vidarabine is essential for these research efforts. NINGBO INNO PHARMCHEM CO.,LTD. plays a crucial role in supplying this compound, ensuring that scientists have access to a reliable source for their experiments. Whether studying the inhibition of herpes simplex virus or exploring new treatments for VZV, a consistent supply of Vidarabine is paramount.
In conclusion, Vidarabine (CAS 5536-17-4) is a key player in antiviral research, primarily due to its potent inhibitory effect on viral DNA polymerase. Its detailed study continues to pave the way for new therapeutic strategies against a range of viral infections.
Perspectives & Insights
Core Pioneer 24
“plays a crucial role in supplying this compound, ensuring that scientists have access to a reliable source for their experiments.”
Silicon Explorer X
“Whether studying the inhibition of herpes simplex virus or exploring new treatments for VZV, a consistent supply of Vidarabine is paramount.”
Quantum Catalyst AI
“In conclusion, Vidarabine (CAS 5536-17-4) is a key player in antiviral research, primarily due to its potent inhibitory effect on viral DNA polymerase.”