Ac-Ala-OH: Understanding Its Chemical Properties and Biological Significance
N-Acetyl-L-Alanine (Ac-Ala-OH) is a molecule that holds significant importance in the scientific community, particularly within biochemistry and organic chemistry. As a derivative of the amino acid alanine, it inherits fundamental properties while gaining new functionalities that make it valuable for various applications, most notably in peptide synthesis. Understanding the precise chemical makeup and biological implications of Ac-Ala-OH is key to leveraging its potential effectively.
At its core, Ac-Ala-OH is N-acetylated L-alanine. The acetyl group (CH3CO-) attached to the alpha-amino group modifies the reactivity of alanine. This modification serves as a protective measure in peptide synthesis, preventing the amino group from participating in unintended reactions during the sequential addition of amino acids to a growing peptide chain. The presence of this acetyl group is crucial for controlled synthesis, ensuring the integrity of the desired peptide sequence.
The chemical identity of Ac-Ala-OH is defined by its molecular formula, C5H9NO3, and a molecular weight of 131.13 g/mol. These specifications are vital for accurate stoichiometric calculations in reactions and for identifying the correct compound during procurement. The CAS number, 97-69-8, provides a universally recognized identifier for this chemical substance, facilitating its lookup in scientific literature, databases, and supplier catalogs. The substance is typically presented as a white crystal solid, indicating a stable, crystalline structure at room temperature.
Beyond its role in synthesis, the parent amino acid, alanine, has recognized biological functions. Alanine is a non-essential amino acid, meaning the human body can synthesize it. It participates in the glucose-alanine cycle, a metabolic pathway that facilitates the transport of amino groups from peripheral tissues to the liver and provides glucose for energy. As a glucogenic amino acid, its carbon skeleton can be converted into glucose, supporting energy homeostasis. While Ac-Ala-OH is primarily used exogenously, the biological relevance of alanine underscores the importance of such amino acid derivatives in metabolic understanding.
Researchers and chemical manufacturers often seek to buy N-Acetyl-L-Alanine for its role in creating complex peptides for research, diagnostics, and therapeutics. The Ac-Ala-OH price can vary depending on the supplier, purity, and quantity, making informed purchasing decisions important. Access to reliable Ac-Ala-OH suppliers ensures that consistent quality material is available for ongoing projects.
In essence, N-Acetyl-L-Alanine is more than just a chemical compound; it is a vital tool that bridges fundamental amino acid chemistry with advanced synthetic applications. Its well-defined properties and biological connections make it a subject of continued interest and utility in scientific research and development.
Perspectives & Insights
Quantum Pioneer 24
“Beyond its role in synthesis, the parent amino acid, alanine, has recognized biological functions.”
Bio Explorer X
“It participates in the glucose-alanine cycle, a metabolic pathway that facilitates the transport of amino groups from peripheral tissues to the liver and provides glucose for energy.”
Nano Catalyst AI
“As a glucogenic amino acid, its carbon skeleton can be converted into glucose, supporting energy homeostasis.”