N-Acetyl-L-Alanine (Ac-Ala-OH) is a chemical compound of significant practical importance, particularly within the domains of organic chemistry and biochemistry. As a derivative of the amino acid alanine, it offers a protected form that is exceptionally useful for controlled synthesis, most notably in the creation of peptides. This guide provides a practical overview of Ac-Ala-OH, covering its fundamental properties, how it is used, and considerations for obtaining it.

The essence of Ac-Ala-OH lies in its chemical structure. It is formed by attaching an acetyl group (CH3CO-) to the amino group of L-alanine. This structural modification, denoted by the N-acetyl component, serves as a protective measure. In the complex processes of peptide synthesis, where amino acids are linked sequentially, protecting the reactive amino terminus is crucial to prevent unwanted side reactions and ensure the correct sequence is built. This makes Ac-Ala-OH an invaluable reagent for chemists aiming for precision in their syntheses.

Key identifiers for Ac-Ala-OH include its CAS number, 97-69-8, which is a unique numerical label used globally to identify this specific chemical substance. Its molecular formula is C5H9NO3, and its molecular weight is approximately 131.13 g/mol. These pieces of information are vital for any researcher or manufacturer to accurately identify, quantify, and utilize the compound in their processes. The physical appearance of Ac-Ala-OH is typically described as a white crystal solid, which is a common and stable form for many organic reagents.

The primary practical application of Ac-Ala-OH is in solid-phase peptide synthesis (SPPS) and solution-phase peptide synthesis. It acts as a building block, ready to be coupled to a growing peptide chain. The N-acetyl group can be removed later in the synthesis if needed, or it can remain as a permanent modification to the peptide's N-terminus, often conferring increased stability against degradation. For those looking to buy N-Acetyl-L-Alanine, understanding these applications helps in determining the required purity and quantity.

Beyond synthesis, the parent amino acid, alanine, is involved in various metabolic processes, including energy production. While Ac-Ala-OH is not typically consumed for its metabolic benefits, its connection to alanine highlights the fundamental importance of amino acids in biological systems. The availability of Ac-Ala-OH from various Ac-Ala-OH suppliers ensures that researchers can access this compound for a wide range of biochemical studies and custom synthesis projects. The Ac-Ala-OH price can vary, making it sensible to compare offerings from different vendors to find the best value for your specific needs.

In summary, N-Acetyl-L-Alanine is a practically important chemical compound whose utility is rooted in its well-defined chemical structure and protective functional group. Its application in peptide synthesis and broader biochemical research makes it a key reagent for scientific advancement.