The Science Behind N-Acetyl-L-Alanine: Properties, Synthesis, and Market Trends
N-Acetyl-L-Alanine (Ac-Ala-OH) stands as a cornerstone compound in modern chemical and biological sciences, primarily recognized for its indispensable role in peptide synthesis. However, its significance extends to its fundamental chemical properties, its biological relevance through its parent amino acid, and the market dynamics surrounding its production and procurement. A comprehensive understanding of Ac-Ala-OH involves appreciating its science, its application, and its availability.
Chemically, Ac-Ala-OH is the N-acetylated derivative of L-alanine. This acetylation, the addition of an acetyl group to the alpha-amino nitrogen, is a common strategy in organic chemistry to protect reactive functional groups. In the context of peptide synthesis, this protection ensures that the amino terminus of alanine remains unreactive during coupling reactions, allowing for the controlled stepwise assembly of peptide chains. The precise molecular formula C5H9NO3 and molecular weight of 131.13 g/mol are critical parameters for its correct identification and quantitative use. The compound's CAS number, 97-69-8, serves as its unique global identifier.
The synthesis of Ac-Ala-OH typically involves the acetylation of L-alanine using reagents such as acetic anhydride or acetyl chloride. These reactions are generally straightforward, yielding the desired product, which is then purified to meet stringent quality standards. The availability of Ac-Ala-OH as a white crystal solid is indicative of its crystalline form, which aids in purification and handling. The Ac-Ala-OH price is influenced by factors such as synthesis efficiency, raw material costs, purity levels, and the scale of production. Sourcing this compound involves looking for reliable Ac-Ala-OH suppliers who can provide materials that meet the specific purity requirements for research or industrial applications.
Biologically, alanine, the parent amino acid, is known for its role in metabolism. It is a glucogenic amino acid, meaning it can be converted into glucose by the body, thus contributing to energy production. It also plays a part in the transport of ammonia and participates in various enzymatic reactions. While Ac-Ala-OH itself is primarily used as a synthetic reagent, the biological functions of alanine highlight the importance of these amino acid derivatives within the broader context of biochemistry and physiology.
The market for Ac-Ala-OH is driven by the burgeoning peptide therapeutics sector, diagnostic development, and academic research. As the demand for complex peptides grows, so does the need for high-quality building blocks like Ac-Ala-OH. Companies that offer Ac-Ala-OH also often provide a wide array of other amino acid derivatives and peptide synthesis reagents, positioning themselves as comprehensive solution providers for the life sciences industry. When intending to buy N-Acetyl-L-Alanine, it is prudent to research multiple suppliers to compare product offerings, pricing, and delivery capabilities.
In essence, N-Acetyl-L-Alanine is a critical molecule whose scientific underpinnings, synthetic utility, and market presence are deeply intertwined. Its careful study and sourcing are essential for advancing research and development in the fields it serves.
Perspectives & Insights
Data Seeker X
“This acetylation, the addition of an acetyl group to the alpha-amino nitrogen, is a common strategy in organic chemistry to protect reactive functional groups.”
Chem Reader AI
“In the context of peptide synthesis, this protection ensures that the amino terminus of alanine remains unreactive during coupling reactions, allowing for the controlled stepwise assembly of peptide chains.”
Agile Vision 2025
“13 g/mol are critical parameters for its correct identification and quantitative use.”