NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of supplying high-quality chemical building blocks essential for scientific advancement. Among these, Fmoc-Orn(Z)-OH stands out as a critical reagent in the field of peptide synthesis. This article aims to illuminate the significance of Fmoc-Orn(Z)-OH, its diverse applications, and the importance of reliable sourcing for researchers and pharmaceutical companies.

Fmoc-Orn(Z)-OH, identified by its CAS number 138775-07-2, is a derivative of the amino acid ornithine. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a base-labile protecting group for the alpha-amino function, a standard in solid-phase peptide synthesis (SPPS). The 'Z' in Fmoc-Orn(Z)-OH refers to the benzyloxycarbonyl (Cbz) protecting group on the side chain of ornithine. This dual protection strategy is crucial for selectively building peptide chains, ensuring that reactions occur at the desired sites without unwanted side reactions.

The primary utility of Fmoc-Orn(Z)-OH lies in its ability to be incorporated into growing peptide chains during SPPS. The Fmoc group can be readily removed by mild basic conditions, allowing the next amino acid to be coupled. The Z group on the ornithine side chain provides orthogonal protection, meaning it can be removed under different conditions (typically acidic or hydrogenolysis), offering flexibility in synthetic strategies. This precise control is vital for creating peptides with specific sequences and functionalities, which are essential for drug discovery, diagnostics, and material science.

Researchers frequently inquire about the Fmoc-Orn(Z)-OH price and seek reliable Fmoc-Orn(Z)-OH suppliers to ensure project continuity and budget adherence. NINGBO INNO PHARMCHEM CO.,LTD. understands these needs and is committed to providing competitive pricing and consistent product availability. The meticulous Fmoc-Orn(Z)-OH synthesis carried out by reputable manufacturers ensures the high purity required for sensitive peptide synthesis protocols, minimizing the risk of failed reactions or impurities in the final peptide product.

Beyond its fundamental role in peptide synthesis, Fmoc-Orn(Z)-OH has found applications in areas such as antifungal evaluation. It serves as an intermediate in the synthesis of cyclic aminohexapeptides and related peptide derivatives that exhibit various biological activities. This demonstrates the compound's versatility and importance in broader medicinal chemistry research. Understanding the various Fmoc-Orn(Z)-OH applications allows scientists to explore new avenues for therapeutic development.

For those looking to purchase Fmoc-Orn(Z)-OH, engaging with established chemical suppliers like NINGBO INNO PHARMCHEM CO.,LTD. is paramount. They not only offer the product but also provide technical support and ensure that the material meets stringent quality standards. The demand for high-quality peptide synthesis reagents continues to grow as research in proteomics and drug development intensifies. Fmoc-Orn(Z)-OH remains a cornerstone in this rapidly advancing field.

In conclusion, Fmoc-Orn(Z)-OH is an indispensable amino acid derivative for peptide synthesis. Its specific protection groups and chemical stability make it a preferred choice for researchers worldwide. NINGBO INNO PHARMCHEM CO.,LTD. plays a key role in making this vital compound accessible, supporting innovation in life sciences and pharmaceuticals.