The efficacy of any pharmaceutical drug is fundamentally linked to the precise chemical nature of its Active Pharmaceutical Ingredient (API). Amiloride Hydrochloride Dihydrate, a vital compound in treating conditions like hypertension and congestive heart failure, is no exception. Understanding its chemical properties and the intricacies of its synthesis is crucial for both pharmaceutical manufacturers and researchers.

Amiloride Hydrochloride Dihydrate is characterized by its specific molecular formula, C6H13Cl2N7O3, and a molecular weight of approximately 302.12 g/mol. Its chemical name, 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochloride dihydrate, highlights its structure as a pyrazine derivative with an amidine group. The presence of the hydrochloride salt and dihydrate form contributes to its stability and solubility, making it suitable for pharmaceutical formulations.

The synthesis of Amiloride Hydrochloride involves a multi-step chemical process, often starting from simpler pyrazine precursors. Key steps typically include the introduction of amino groups, a chlorine atom, and the carboxamide side chain with the amidine moiety. Achieving high purity and yield requires careful control of reaction conditions, reagents, and purification techniques. The detailed Amiloride hydrochloride chemical structure dictates its biological activity, specifically its ability to block epithelial sodium channels.

For companies seeking to purchase Amiloride hydrochloride, understanding the synthesis process is important for ensuring product quality and consistency. NINGBO INNO PHARMCHEM CO.,LTD. specializes in the synthesis of complex pharmaceutical intermediates and APIs, including Amiloride Hydrochloride Dihydrate. Their expertise ensures that the manufactured API meets stringent purity standards required for pharmaceutical applications.

The Amiloride hydrochloride API is supplied with comprehensive technical documentation, including Certificates of Analysis (CoA), which detail the purity, identity, and impurity profile of the compound. This information is critical for regulatory submissions and quality control procedures during drug formulation. NINGBO INNO PHARMCHEM CO.,LTD. provides detailed specifications for their Amiloride Hydrochloride Dihydrate, reflecting their commitment to transparency and quality.

In conclusion, Amiloride Hydrochloride Dihydrate is a complex molecule whose therapeutic value is directly tied to its precise chemical composition and synthesis. The expertise of suppliers like NINGBO INNO PHARMCHEM CO.,LTD. in manufacturing this API ensures that the pharmaceutical industry has access to a high-quality ingredient essential for treating critical cardiovascular conditions. Their dedication to chemical synthesis excellence supports the development of effective and safe medicines globally.